Category: 18928-94-4

Burschkies, Karl published the artcileThe importance of cyclic acids and alcohols for the chemotherapy of leprosy, Application In Synthesis of 18928-94-4, the publication is Archiv der Pharmazie und Berichte der Deutschen Pharmazeutischen Gesellschaft (1943), 328-36, database is CAplus.

New cyclopentyl derivatives are prepared and their effect on rat leprosy is examined Refluxing 23 g. Na, 130 g. AcCH₂CO₂Et in 500 cc. xylene, and 149 g. freshly distilled cyclopentyl bromide for 20 hrs. at 140° gives Et cyclopentaneacetoacetate (I), b₁₂ 120-2°, n²⁰_D 1.4646. Refluxing 198 g. of I with 23 g. Na in 600 cc. absolute alc. for several hrs. gives Et cyclopentaneacetate (II), b₁₂ 74-5°, n²⁰_D 1.4357. II (156 g.) in 1200 cc. absolute alc. treated with 100 g. Na gives cyclopentaneëthanol (III), b₁₃ 80-1°, n¹⁹_D 1.4572. Saponification of II during the previous reaction transforms part of it into cyclopentaneacetic acid (IV) which is isolated by acidifying, shaking with Et₂O, washing and drying over Na₂SO₄, b₁₃ 119-20°, n¹⁹_D 1.4527. Treating IV with SOCl₂ at 0°, heating to 70° for 1/2 hr., and distilling off the SOCl₂ gives cyclopentaneacetyl chloride, b₁₂ 60°, which is reacted with hydnocarpic alc. to form hydnocarpyl cyclopentaneacetate (V), b_0.02 205-10°, n²⁰_D 1.4720. Adding PBr₃ to III in toluene gives 2-cyclopentylethyl bromide (VI), b. 78-9°, n²⁰_D 1.4866. After combining finely powd. Na with CH₂(CO₂Et)₂ in xylene solution VI is added. By refluxing for 24 hrs. at 130° di-Et (2-cyclopentylethyl)malonate (VII) is formed, b₁₃ 158-60°, n²²_D 1.4470. By saponification of VII (2-cyclopentylethyl)malonic acid, m. 120°, and by subsequent decarboxylation at 15 mm. and 200° cyclopentanebutyric acid (VIII), b_0.0-80.1 115-17°, n²⁰_D 1.4579, are formed. By heating VIII with benzyl alc. in a N atm. for 6 hrs. at 160-80°, taking up with Et₂O, and shaking with 4% KOH benzyl cyclopentanebutyrate, b_0.05, 138-40°, n²¹_D 1.5248, is formed. Esterification of VIII with EtOH gives the Et ester (IX), b_0.08 75°, n²⁰_D 1.4433. By reduction of IX with Na and absolute alc. cyclopentanebutanol (X), b₁₂ 109-10°, n²²_D 1.4610, is formed. Reacting X in toluene with freshly distilled PBr₃ gives 4-cyclopentylbutyl bromide (XI), b₁₅ 107°, n²²_D 1.4815, which gives with CH₂(CO₂Et)₂ and Na di-Et(4-cyclopentylbutyl)malonate (XII), b_0.1 140-2°, n²²_D 1.4494. By saponification of XII (4-cyctopentylbutyl)malonic acid, m. 125-6°, and by further decarboxylation cyclopentanecaproic acid (XIII), b_0.1 133°, m. 36-7°, are formed. By heating XIII in N for 4 hrs. with benzyl alc. to 190-200° the benzyl ester, b_0.1 163°, n²¹_D 1.5010, is obtained. Esterification of XIII with EtOH gives the Et ester, b₁₂ 136-7°, n²²_D 1.4462, which is reduced by Na to cyclopentanehexanol (XIV), b₁₂ 130-2°, n²⁰_D 1.4630. Esterification of III, X, XIV with PhCH:CHCOCl gives 2-cyclopentylethyl cinnamate, b_0.1 188°, n²⁰_D 1.5521, 4-cyclopentylbutyl cinnamate, b_0.1 190°, n_21D 1.5428, 6-cyclopentylhexyl cinnamate, b_0.0 190°, n_20D 1.5372. The study of the therapeutic effect of cyclopentyl compounds shows that compounds with over 3 CH₂-groups are effective on rat leprosy. The cyclopentyl compounds are better tolerated than the corresponding cyclopentenyl compounds The cinnamic esters of III, X, XIV show a very good therapeutic effect on rat leprosy.

Archiv der Pharmazie und Berichte der Deutschen Pharmazeutischen Gesellschaft published new progress about 18928-94-4. 18928-94-4 belongs to bromides-buliding-blocks, auxiliary class Bromide,Aliphatic cyclic hydrocarbon, name is (2-Bromoethyl)cyclopentane, and the molecular formula is C7H13Br, Application In Synthesis of 18928-94-4.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Goryaev, M. I. published the artcileSynthesis of cyclopentane carbocylic acids, HPLC of Formula: 18928-94-4, the publication is Trudy Instituta Khimicheskikh Nauk, Akademiya Nauk Kazakhskoi SSR (1967), 77-87, database is CAplus.

C5H9 = cyclopentyl throughout this abstract A homologous series of cyclopentanecarboxylic acids of the general type I was synthesized and their ir spectra studied. Grignard reaction between C5H9Br and CO2 yielded 45% I (n = 0), b2 83°, n20D 1.4535. Treatment of di-Et Na malonate with C5H9Br gave 60% di-Et cyclopentanemalonate, b3 130-2°, n20D 1.4430, converted into the free acid and decarboxylated to yield I (n = 1), b3 93°, n20D 1.4522. Grignard reagent prepared from 140 g. C5H9Br and 9 g. Mg was treated at -10° with 20 g. ethylene oxide in 35 ml. ether to yield a distillation fraction containing crude C5H9(CH2)2OH, brominated to give 71% C5H9(CH2)2Br, b19 75-7°, n20D 1.4860; treatment with KCN yielded 53% corresponding nitrile, b2-3 62-8°, n20D 1.4500; hydrolysis of this gave 65.4% I (n = 2), b2 96-7°, n20D 1.4563. Condensation of C5H9(CH2)2Br with di-Et Na malonate yielded 30% di-Et (2-cyclopentylethyl)malonate, b2 136-8°, n20D 1.4442, decarboxylation of which gave 90% I (n = 3), b7 145-50°, n20D 1.4518. Cyclopentanebutanol, b2 85-6°, n20D 1.4610, d2020 0.9033; C5H9(CH2)4Br, b17 110-12°, n20D 1.4820, d2020 1.1872; C5H9(CH2)4CN, b17 124-6°, n20D 1.4575; and I (n = 4), b2 124-8°, n20D 1.4595, d2020 0.9752, were obtained from C5H9(CH2)2Br and ethylene oxide as starting materials in 55, 64, 88, and 81% yields, resp. Reaction between C5H9(CH2)4Br and di-Et Na malonate yielded 49.3% di-Et (4-cyclopentylbutyl)malonate, which on decarboxylation gave 69.7% I (n = 5), b2 127-30°, n20D 1.4542, d2020 0.9520. A mixture of air and ozone was passed through a solution of 60 g. Me oleate in AcOEt until neutral to reaction with Br; to the cooled solution 4 g. Zn dust in 2 ml. H2O was added, followed by 36 g. Zn in small portions and 4 ml. H2O on completion of the reaction; the mixture was stirred until neutral to the KI-starch test and worked up to yield 70% Me 8-formyloctanoate (II), b2 113°, n20D 1.4380. Grignard reaction between C5H9(CH2)2Br and II yielded 20% Me 11-cyclopentyl-9-hydroxyundecanoate; C5H9(CH2)4Br and II gave 15% Me 13-cyclopentyl-9-hydroxytridecanoate. Extensive ir data were given.

Trudy Instituta Khimicheskikh Nauk, Akademiya Nauk Kazakhskoi SSR published new progress about 18928-94-4. 18928-94-4 belongs to bromides-buliding-blocks, auxiliary class Bromide,Aliphatic cyclic hydrocarbon, name is (2-Bromoethyl)cyclopentane, and the molecular formula is C7H13Br, HPLC of Formula: 18928-94-4.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Venkateswararao, Eeda published the artcileAnti-proliferative effect of chalcone derivatives through inactivation of NF-κB in human cancer cells, SDS of cas: 18928-94-4, the publication is Bioorganic & Medicinal Chemistry (2014), 22(13), 3386-3392, database is CAplus and MEDLINE.

To investigate the anti-proliferative effect of NF-κB inhibitor, a series of analogs of (E)-1-(2-hydroxy-6-(isopentyloxy)phenyl)-3-(4-hydroxyphenyl)prop-2-en-1-one were prepared and evaluated for their NF-κB inhibition and anti-proliferative activity against various human cancer cell lines. Compounds (E)-1-(2-(3,3-dimethylbutoxy)-6-hydroxyphenyl)-3-(4-hydroxyphenyl)prop-2-en-1-one and (E)-4-(3-(2-(3,3-dimethylbutoxy)-6-hydroxyphenyl)-3-oxoprop-1-enyl)benzenesulfonamide showed good NF-κB inhibition as well as potent anti-proliferative activity. SAR studies showed that all the compounds with potent or moderate NF-κB inhibition displayed good anti-proliferative activity. All the analogs maintained a good correlation between their NF-κB inhibition and anti-proliferative activity though the extent is not directly proportional to each other.

Bioorganic & Medicinal Chemistry published new progress about 18928-94-4. 18928-94-4 belongs to bromides-buliding-blocks, auxiliary class Bromide,Aliphatic cyclic hydrocarbon, name is (2-Bromoethyl)cyclopentane, and the molecular formula is C13H19Br2ClN2O, SDS of cas: 18928-94-4.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Tang, Nana published the artcilePractical, metal-free remote heteroarylation of amides via unactivated C(sp³)-H bond functionalization, Application of (2-Bromoethyl)cyclopentane, the publication is Chemical Science (2019), 10(28), 6915-6919, database is CAplus and MEDLINE.

A new, efficient, site-selective heteroarylation of amides via C(sp³)-H bond functionalization. Amidyl radicals were directly generated from the amide N-H bonds under mild conditions, which triggered the subsequent 1,5-HAT process. A wide scope of aliphatic amides including carboxamides, sulfonamides and phosphoramides were readily modified at remote C(sp³)-H bonds by installing diverse heteroaryl groups. Borne out of pragmatic consideration, this protocol was used for the late-stage functionalization of amides.

Chemical Science published new progress about 18928-94-4. 18928-94-4 belongs to bromides-buliding-blocks, auxiliary class Bromide,Aliphatic cyclic hydrocarbon, name is (2-Bromoethyl)cyclopentane, and the molecular formula is C3H9ClOS, Application of (2-Bromoethyl)cyclopentane.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Chen, Ying published the artcileStructure-activity relationship studies of (E)-3,4-dihydroxystyryl alkyl sulfones as novel neuroprotective agents based on improved antioxidant, anti-inflammatory activities and BBB permeability, Name: (2-Bromoethyl)cyclopentane, the publication is European Journal of Medicinal Chemistry (2019), 420-433, database is CAplus and MEDLINE.

(E)-3,4-dihydroxystyryl alkyl sulfones I [n = 0, 1, 2; R = Et, Pr, Bu, etc.], as new analogs of neurodegenerative agents, were designed and synthesized. The biol. results demonstrated that most of the target compounds preserved antioxidant and anti-inflammatory potency in scavenging reactive free radicals, protecting neuronal cells against neurotoxins such as H₂O₂, 6-hydroxydopamine and inhibiting lipopolysaccharide (LPS)-induced over-production of NO. Among these compounds, I [n = 2; R = cyclopentyl] exhibited prominent antioxidant activity at low concentration (2.5 μM) in H₂O₂ model (cell viability = 94.5%). In addition, I [n = 2; R = cyclopentyl] (IC₅₀ = 1.6 μM) displayed better anti-inflammatory activity than that of lead compound 1 (IC₅₀ = 13.4 μM). In view of the outstanding performance of I [n = 2; R = cyclopentyl], the apoptotic rates of H₂O₂-damaged PC12 cells were detected by Annexin V-FITC/PI assay. I [n = 2; R = cyclopentyl] showed higher potency in inhibition of apoptosis than 1 at low concentration (2.5 μM), consisting with the antioxidant and anti-inflammatory models. Furthermore, with the predicted CNS (+) blood-brain barrier (BBB) permeability (Pe = 6.84 x 10^-6 cm s^-1), low cytotoxicity and favorable physiochem. properties based on calculation, compound I [n = 2; R = cyclopentyl] can be further developed as a potential multifunctional neuroprotective agent.

European Journal of Medicinal Chemistry published new progress about 18928-94-4. 18928-94-4 belongs to bromides-buliding-blocks, auxiliary class Bromide,Aliphatic cyclic hydrocarbon, name is (2-Bromoethyl)cyclopentane, and the molecular formula is C7H13Br, Name: (2-Bromoethyl)cyclopentane.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Lednicer, Daniel published the artcile4-Amino-4-arylcyclohexanones and their derivatives: a novel class of analgesics. 2. Modification of the carbonyl function, Quality Control of 18928-94-4, the publication is Journal of Medicinal Chemistry (1981), 24(4), 404-8, database is CAplus and MEDLINE.

The cyclohexanols I (R = H, alkyl, alkenyl, alkynyl, PhCH₂, PhCH₂CH₂, etc.; R¹ = H, Cl, Br, Me), prepared by the reduction of or addition of nucleophiles to the corresponding cyclohexanones, were separated into cis and trans isomers and tested for analgesic activity. The trans (OH and N) isomers were invariably more potent than the cis. I (R = PhCH₂CH₂) are among the most potent opioids reported to date; possibly the ring system may be providing an addnl. binding site for these compounds, and thus greatly enhance their affinity for the opioid receptor.

Journal of Medicinal Chemistry published new progress about 18928-94-4. 18928-94-4 belongs to bromides-buliding-blocks, auxiliary class Bromide,Aliphatic cyclic hydrocarbon, name is (2-Bromoethyl)cyclopentane, and the molecular formula is C7H13Br, Quality Control of 18928-94-4.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Pilat, S. published the artcileFormation of cyclopentylalkanesulfonates, Product Details of C7H13Br, the publication is Berichte der Deutschen Chemischen Gesellschaft [Abteilung] B: Abhandlungen (1939), 1527-31, database is CAplus.

The Na naphthenesulfonates obtained from natural naphthenic acids through the naphthenyl alcs. and chlorides (C. A. 32, 8753.5) are characterized by their excellent foaming and wetting properties in aqueous solution For comparison with these substances, whose structure has not been fully cleared up, P. and T. undertook the preparation of some cyclic sulfonates (chiefly cyclopentane derivatives, since the naphthenic acids in petroleums are for the most part derived from cyclopentane) in which the sulfonic acid is in primary combination, i. e., as CH₂SO₃H. The starting point for the preparation of sulfonates with a straight alkyl chain, C₅H₉(CH₂)_nSO₃Na (n = 2, 4 or 7) was cyclopentanol, which was converted with boiling concentrated HCl and CaCl₂ into the chloride (87% yield); this through the Grignard reagent with HCHO gave the carbinol, C₅H₉CH₂OH, which, in turn, was converted into the chloride. 2-Cyclopentylethanol (I) and 4-cyclopentylbutanol (II), as also 2-menthylethanol (III), were prepared by the Grignard method for introducing CH₂.CH₂ chains: RMgBr + CH₂.CH₂.O → RCH₂CH₂OMgBr. Chains of 3 CH₂ groups were introduced by treating Grignard compounds with p-MeC₆H₄SO₃(CH₂)₃Cl (IV) or with trimethylene oxide; in this way (7-chloroheptyl)cyclopentane (V) was prepared from C₅H₉(CH₂)₄Br and II from C₅H₉CH₂Cl. For the preparation of sulfonates with a branched chain fenchone was used, which was converted by KOH at 240° into fencholic acid (VI). Reduction of the Et ester of VI gave fencholyl alc. (VII), converted with PCl₅ into the chloride, which with Na₂SO₃ gave 50% Na fencholylsulfonate and, through fencholylmalonic acid, yielded fencholylacetic acid (VIII). Reduction of the Et ester of VIII, conversion of the 2-fencholylethanol (IX) into the chloride and subsequent Strecker reaction yielded Na fencholylethanesulfonate (50% yield), very hygroscopic. Investigation of aqueous solutions of the Na salts so obtained, which will be described in detail later, showed, among other things, that sulfonates in which a cyclopentane ring carries small alkyl groups are characterized by an especially high degree of surface activity and in this respect surpass both cyclopentanes with a long side chain and alkylated cyclohexanes. I, b₁₁ 85°, was obtained in 45% yield by a modification of the Yohe and Adams method (C. A. 22, 2148). Chloride (71% from I and 1.1 mols. PCl₅ refluxed 2 h. in petr. ether), b₆₀ 85-6°, d₄²⁰ 0.955, n_D²⁰ 1.4527; 26.5 g. heated 8 h. at 200° with 80 g. crystallized Na₂SO₃ in an autoclave, with stirring, gave 39 g. (97.5%) Na 2-cyclopentylethanesulfonate, silvery non-hygroscopic needles. (2-Bromoethyl)cyclopentane (71.2% from I heated 2.5 h. with HBr-concentrated H₂SO₄), b₁₉ 77°, d₄²⁰ 1.290, n_D²⁰ 1.4865; its Grignard reagent with ethylene oxide gave 68% II, b₂ 87-92°, n_D²⁰ 1.4610, d₄²⁰ 0.903 (from C₅H₉CH₂Cl and trimethylene oxide the yield was only 5%). (4-Bromobutyl)cyclopentane (90% from II with HBr-H₂SO₄), b₁₇ 110-11°, n_D²⁰ 1.4820, d₄²⁰ 1.187, gives with Na₂SO₃ after 8 h. at 160° in a rotating autoclave Na 4-cyclopentylbutanesulfonate. V (10% from C₅H₉(CH₂)₄Br and IV), b. 120-5°; Na 7-cyclopentylheptanesulfonate, strongly hygroscopic. Menthyl bromide (80% from menthol and HBr-H₂SO₄), b₁₃ 105.5°, d₄²⁰ 1.162, n_D²⁰ 1.4852. III (20%), b₁₀ 132-6°; chloride (35%), b₁₀ 120-5°; Na 2-menthylethanesulfonate. VII (84.5%), b₁₀ 96.5°, [α]_D 8.6°; chloride, b₉ 84°, d₄^21.5 0.949, n_D¹⁷ 1.4702. VIII (46%), b₁₀ 165-6°; Et ester, b₁₀ 146-8°. IX (5% from the Grignard compound of fencholyl chloride with ethylene oxide, or 76% by reduction of the Et ester of VIII with Na in absolute alc.), b₁₀ 134-5°, n_D¹⁸ 1.4761; chloride (65%), b₁₀ 120-6°.

Berichte der Deutschen Chemischen Gesellschaft [Abteilung] B: Abhandlungen published new progress about 18928-94-4. 18928-94-4 belongs to bromides-buliding-blocks, auxiliary class Bromide,Aliphatic cyclic hydrocarbon, name is (2-Bromoethyl)cyclopentane, and the molecular formula is C7H13Br, Product Details of C7H13Br.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Fujiki, Michiya published the artcileThermo-driven chiroptical switching polysilane featuring 2-cyclopentylethyl side group, Recommanded Product: (2-Bromoethyl)cyclopentane, the publication is Silicon Chemistry (2002), 1(1), 67-72, database is CAplus.

A new rod-like helical polysilane, poly{(S)-3,7-dimethyloctyl(2-cyclopentylethyl)silane}, was found to undergo a thermo-driven, helix-helix transition at -33°C in isooctane associated with the discontinuous changes in the Siσ-Siσ* transition energy and intensity in the transition temperature region. This is the first example of a helix-helix transition polysilane with a cycloalkyl group. A similar rod-like polysilane derivative, poly{(S)-3,7-dimethyloctyl(1-cyclopentylmethyl)silane}, however, did not undergo any helix-helix transition between -61 and 80°C.

Silicon Chemistry published new progress about 18928-94-4. 18928-94-4 belongs to bromides-buliding-blocks, auxiliary class Bromide,Aliphatic cyclic hydrocarbon, name is (2-Bromoethyl)cyclopentane, and the molecular formula is C7H13Br, Recommanded Product: (2-Bromoethyl)cyclopentane.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Hu, Essa published the artcileDiscovery of Aryl Aminoquinazoline Pyridones as Potent, Selective, and Orally Efficacious Inhibitors of Receptor Tyrosine Kinase c-Kit, Related Products of bromides-buliding-blocks, the publication is Journal of Medicinal Chemistry (2008), 51(11), 3065-3068, database is CAplus and MEDLINE.

Inhibition of c-Kit has the potential to treat mast cell associated fibrotic diseases. We report the discovery of several aminoquinazoline pyridones that are potent inhibitors of c-Kit with greater than 200-fold selectivity against KDR, p38, Lck, and Src. In vivo efficacy of pyridone 16 (I)by dose-dependent inhibition of histamine release was demonstrated in a rodent pharmacodynamic model of mast cell activation.

Journal of Medicinal Chemistry published new progress about 18928-94-4. 18928-94-4 belongs to bromides-buliding-blocks, auxiliary class Bromide,Aliphatic cyclic hydrocarbon, name is (2-Bromoethyl)cyclopentane, and the molecular formula is C7H13Br, Related Products of bromides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Shepard, Edwin R. published the artcilePapaverine analogs. IV. 1-Cycloalkyl-6,7-dimethoxyisoquinolines, Related Products of bromides-buliding-blocks, the publication is Journal of Organic Chemistry (1954), 415-18, database is CAplus.

cf. C.A. 47, 9970f. A number of 1-cycloalkylisoquinolines related to papaverine have been prepared for pharmacol. evaluation. Reduction of 120 g. Et cyclopentylacetate in 120 cc. ether with 20 g. LiAlH₄ in 100 cc. ether gives 82% β-cyclopentylethanol, b₂₃ 94-5°, which (72 g.), treated with an excess of anhydrous HBr, gives 99% β-cyclopentylethyl bromide (I), b₁₉ 76-8°. Adding 111 g. I to 62 g. NaCN in 125 cc. H₂O and 250 cc. Methyl Cellosolve with stirring and refluxing, refluxing the mixture 6 hrs., diluting it with H₂O, and extracting with ether give 80% β-cyclopentylpropionitrile, b₁₉ 98-100°, n_D²⁵ 1.4490, which (40 g.), refluxed 12 hrs. with 300 cc. 25% NaOH, gives 92% β-cyclopentylpropionic acid, b₁₄ 134-6°. Heating 36.2 g. homoveratrylamine and 22.8 g. cyclopentanecarboxylic acid 1 hr. at 190-200° in an open flask gives 73% N-homoveratrylcyclopentanecarboxamide, m. 95.5-6.5°. Similarly are prepared: N-homoveratrylcyclopentylacetamide, 90%, m. 88-9°; N-homoveratryl-β-cyclopentylpropionamide, 85%, m. 89-90°; N-homoveratrylcyclohexanecarboxamide, 84%, m. 111.5-12.5°; N-homoveratryl-β-cyclohexylpropionamide, 77%, m. 94.5-5.5°. These amides are converted into the following 1-cycloalkyl-6,7-dimethoxyisoquinolines-HCl according to the method described earlier: 1-cyclopentyl, 64%, m. 194-6.5°, coronary dilator and antispasmodic activity (CD) 0.9 (relative to papaverine-HCl as unity); 1-cyclopentylmethyl, 74%, m. 200-2°, CD 0.6; 1-β-cyclopentylethyl, 57%, m. 158-62.5°, CD 1; cyclohexyl, 41%, m. 166-8°, CD 1; 1-β-cyclohexylethyl, 56%, m. 203-4°, CD 0.3.

Journal of Organic Chemistry published new progress about 18928-94-4. 18928-94-4 belongs to bromides-buliding-blocks, auxiliary class Bromide,Aliphatic cyclic hydrocarbon, name is (2-Bromoethyl)cyclopentane, and the molecular formula is C9H8O4, Related Products of bromides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary