Category: 188813-04-9

Hu, Penghui; Tan, Mingxi; Cheng, Lu; Zhao, Hongyuan; Feng, Rui; Gu, Wei-Jin; Han, Wei published the artcile< Bio-inspired iron-catalyzed oxidation of alkylarenes enables late-stage oxidation of complex methylarenes to arylaldehydes>, HPLC of Formula: 188813-04-9, the main research area is alkylarene polymethylhydrosiloxane promoter iron catalyst selective aerobic oxidation; aryl carbonyl compound preparation.

A bio-inspired iron-catalyzed polymethylhydrosiloxane-promoted aerobic oxidation of methylarenes to arylaldehydes with high yields and selectivities was reported. Notably, this method can tolerate oxidation-labile and reactive boronic acid group, which is normally required to be transformed immediately after its introduction and represents a significant advance in the area of the chem. of organoboronic acids, including the ability to incorporate both aldehyde and ketone functionalities into unprotected arylboronic acids, a class that can be difficult to access by current means. The robustness of this protocol was demonstrated on the late-stage oxidation of complex bioactive mols., including dehydroabietic acid, Gemfibrozil, Tocopherol nicotinate, a complex polyol structure and structurally complex arylboronic acids.

Nature Communications published new progress about Air. 188813-04-9 belongs to class bromides-buliding-blocks, and the molecular formula is C8H7BrO, HPLC of Formula: 188813-04-9.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Xu, Chao; Fyfe, James W. B.; Seath, Ciaran P.; Bennett, Steven H.; Watson, Allan J. B. published the artcile< A one-pot tandem chemoselective allylation/cross-coupling via temperature control of a multi-nucleophile/electrophile system>, Reference of 188813-04-9, the main research area is biaryl chemoselective microwave irradiation; haloaryl aldehyde BPin allylation Suzuki Miyaura.

A chemoselective tandem reaction of a multi-reactive, two electrophile + two nucleophile, system was reported. An allylation/cross-coupling process of aryl/allyl BPins e.g., 2-propenylboronic acid pinacol ester, haloaryl aldehydes such as 4-bromobenzaldehyde, 6-bromonicotinaldehyde, (E)-5-iodopent-4-enal, etc. can be controlled using a temperature gradient to overcome natural reactivity profiles and allow two sequential chemoselective C-C bond formations without intervention to afforded biaryls e.g., I scaffold of products. This process offers efficient access to an array of functionalized products including pharmaceutical and natural product scaffolds.

Chemical Communications (Cambridge, United Kingdom) published new progress about Allylation (chemoselective). 188813-04-9 belongs to class bromides-buliding-blocks, and the molecular formula is C8H7BrO, Reference of 188813-04-9.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Evans, P. Andrew; Oliver, Samuel published the artcile< Regio- and Enantiospecific Rhodium-Catalyzed Allylic Substitution with an Acyl Anion Equivalent>, Recommanded Product: 3-Bromo-5-methylbenzaldehyde, the main research area is chiral nonracemic tertiary allylic alc cyanohydrin pronucleophile allylic substitution; acyclic quaternary substituted aryl ketone stereoselective rhodium catalyzed preparation; cyanohydrin acyl anion equivalent stereoselective allylic alkylation pronucleophile.

The construction of enantiomerically enriched acyclic quaternary substituted ketones via the regio- and enantiospecific rhodium-catalyzed allylic alkylation reaction of chiral nonracemic tertiary allylic alcs. with cyanohydrin pronucleophiles is described. This approach provides an alternative method to the α-arylation and vinylation of acyclic disubstituted ketone enolates, which remains a challenging endeavor. The combination of the allylic alkylation with ring-closing metathesis facilitates the preparation of enantiomerically enriched 2,2-disubstituted naphthalene-1-ones, which have proven very difficult to prepare using a more conventional dearomatization strategy.

Organic Letters published new progress about Allylic alkylation catalysts, stereoselective. 188813-04-9 belongs to class bromides-buliding-blocks, and the molecular formula is C8H7BrO, Recommanded Product: 3-Bromo-5-methylbenzaldehyde.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary