18791-79-2 Archives - Bromides-buliding-blocks

Xia, Anjie et al. published their research in Organic Letters in 2019 | CAS: 18791-79-2

Metal-Free Aerobic Oxidative Selective C-C Bond Cleavage in Heteroaryl-Containing Primary and Secondary Alcohols was written by Xia, Anjie;Qi, Xueyu;Mao, Xin;Wu, Xiaoai;Yang, Xin;Zhang, Rong;Xiang, Zhiyu;Lian, Zhong;Chen, Yingchun;Yang, Shengyong. And the article was included in Organic Letters in 2019.Application of 18791-79-2 This article mentions the following:

A transition-metal-free aerobic oxidative selective C-C bond-cleavage reaction in primary and secondary heteroaryl alcs. is reported. This reaction was highly efficient and tolerated various heteroaryl alcs., generating a carboxylic acid derivative and a neutral heteroaromatic compound Exptl. studies combined with d. functional theory calculations revealed the mechanism underlying the selective C-C bond cleavage. This strategy also provides an alternative simple approach to carboxylation reaction. In the experiment, the researchers used many compounds, for example, 5-Bromothiophene-3-carbaldehyde (cas: 18791-79-2Application of 18791-79-2).

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Gao, Li-Bin et al. published their research in Heteroatom Chemistry in 2016 | CAS: 18791-79-2

5-Bromothiophene-3-carbaldehyde (cas: 18791-79-2) belongs to organobromine compounds. Bromine is more electronegative than carbon (2.9 vs 2.5). Consequently, the carbon in a carbon闂佺偨鍎茶ぐ绲﹐mine bond is electrophilic, i.e. alkyl bromides are alkylating agents. Commercially available organobromine pharmaceuticals include the vasodilator nicergoline, the sedative brotizolam, the anticancer agent pipobroman, and the antiseptic merbromin. SDS of cas: 18791-79-2

Studies of Substituents Impact on the Photophysical Properties of 8-Hydroxyquinoline Derivatives was written by Gao, Li-Bin;Kang, Wu-Kui;Yan, Shi-Hai;Yang, Chun-Peng. And the article was included in Heteroatom Chemistry in 2016.SDS of cas: 18791-79-2 This article mentions the following:

Five new 8-hydroxyquinoline derivatives L1-L5 were synthesized and characterized by different techniques, such as NMR, electrospray ionization mass spectra, elemental anal., UV-visible, and photoluminescence spectra. The structure of (E)-2-{2-[5-(phenylethynyl) thiophen-2-yl]ethenyl}quinolin-8-ol (L3) was confirmed by x-ray crystallog. In this structure, intermol. hydrogen bonds were found between OH hydrogen donors of one monomer and the oxygen atom of the next one. Photophys. studies show that different substitutes affect the absorption wavelength and emission color. In the experiment, the researchers used many compounds, for example, 5-Bromothiophene-3-carbaldehyde (cas: 18791-79-2SDS of cas: 18791-79-2).

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Eras, J. et al. published their research in Journal of Heterocyclic Chemistry in 1984 | CAS: 18791-79-2

5-Bromothiophene-3-carbaldehyde (cas: 18791-79-2) belongs to organobromine compounds. Organo bromine compounds are versatile compounds and are widely used in diverse fields. Organo bromine derivatives are used in the dye sector, as an indicator in analytical chemistry (Bromothymol blue is a popular indicator). When the molecular ion is detected, the bromine and chlorine isotope patterns are very distinct, but caution is to be exercised for certain mixed chlorinated/brominated compounds, which can look similar to homohalogen patterns.HPLC of Formula: 18791-79-2

Reactivity of thienopyrroles. Synthesis of isomeric nitro and bromothienopyrroles was written by Eras, J.;Galvez, C.;Garcia, F.. And the article was included in Journal of Heterocyclic Chemistry in 1984.HPLC of Formula: 18791-79-2 This article mentions the following:

The isomeric thienopyrroles I and II (R = H, Br) were prepared by thermal cyclization of the azidothienylacrylates III and IV. III and IV were prepared from the corresponding thiophenecarboxaldehydes and N₃CH₂CO₂Et. I and II (R = NO₂) were prepared by nitration of I and II (R = H). In the experiment, the researchers used many compounds, for example, 5-Bromothiophene-3-carbaldehyde (cas: 18791-79-2HPLC of Formula: 18791-79-2).

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Cheng, Huicheng et al. published their research in Tetrahedron Letters in 2013 | CAS: 18791-79-2

5-Bromothiophene-3-carbaldehyde (cas: 18791-79-2) belongs to organobromine compounds. Bromine is more electronegative than carbon (2.9 vs 2.5). Consequently, the carbon in a carbon閳ユ彽romine bond is electrophilic, i.e. alkyl bromides are alkylating agents. Many of the alkyl bromine derivatives are excellent alkylating agents since bromides are good leaving groups. Tribromides, like tetrabutylammonium tribromide, are used as a solid source of bromine. N-bromosuccimide (NBS) is used for the selective bromination of allylic bonds.Name: 5-Bromothiophene-3-carbaldehyde

Highly efficient synthesis of aryl and heteroaryl trifluoromethyl ketones via o-iodoxybenzoic acid (IBX) was written by Cheng, Huicheng;Pei, Yu;Leng, Faqiang;Li, Jingya;Liang, Apeng;Zou, Dapeng;Wu, Yangjie;Wu, Yusheng. And the article was included in Tetrahedron Letters in 2013.Name: 5-Bromothiophene-3-carbaldehyde This article mentions the following:

A 2-step process for the synthesis of aryl and heteroaryl trifluoromethyl ketones from the corresponding aldehydes is described. Trifluoromethyl alcs. were prepared from aryl and heteroaryl aldehydes in excellent yields using catalytic amounts of K₂CO₃. The trifluoromethyl alcs. were then oxidized conveniently and efficiently by 2-iodoxybenzoic acid (IBX) under mild conditions to give the desired functionalized aryl and heteroaryl trifluoromethyl ketones. In the experiment, the researchers used many compounds, for example, 5-Bromothiophene-3-carbaldehyde (cas: 18791-79-2Name: 5-Bromothiophene-3-carbaldehyde).

5-Bromothiophene-3-carbaldehyde (cas: 18791-79-2) belongs to organobromine compounds. Bromine is more electronegative than carbon (2.9 vs 2.5). Consequently, the carbon in a carbon閳ユ彽romine bond is electrophilic, i.e. alkyl bromides are alkylating agents. Many of the alkyl bromine derivatives are excellent alkylating agents since bromides are good leaving groups. Tribromides, like tetrabutylammonium tribromide, are used as a solid source of bromine. N-bromosuccimide (NBS) is used for the selective bromination of allylic bonds.Name: 5-Bromothiophene-3-carbaldehyde

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Fournari, Pierre et al. published their research in Bulletin de la Societe Chimique de France in 1967 | CAS: 18791-79-2

5-Bromothiophene-3-carbaldehyde (cas: 18791-79-2) belongs to organobromine compounds. Bromo compounds are employed in a variety of metal-catalyzed coupling reactions. They are also ideal candidates for the synthesis of Grignard reagents that have wide-applicability in organic synthesis. alpha-Bromoesters are employed in the Reformatsky reaction for the synthesis of beta-hydroxyesters. One prominent application of synthetic organobromine compounds is the use of polybrominated diphenyl ethers as fire-retardants, and in fact fire-retardant manufacture is currently the major industrial use of the element bromine.Category: bromides-buliding-blocks

Heterocyclics. XIII. Synthesis of substituted bromothiophenes was written by Fournari, Pierre;Guilard, Roger;Person, Maurice. And the article was included in Bulletin de la Societe Chimique de France in 1967.Category: bromides-buliding-blocks This article mentions the following:

Bromothiophenecarboxaldehydes of the general formula I are prepared and treated with aryl ketones to give compounds of the general formula II. Thus, 66 g. 2,3-dibromothiophene is treated with 0.273 mole BuLi and the organic Li compound obtained is treated with 30 g. HCONMe2 to give 13.5 g. 3-bromo-2-formylthiophene (III), b12 109-12鎺? thiosemicarbazone m. 246鎺? oxime m. 159鎺? Similarly prepared are (b.p./mm., m.p., m.p. thiosemicarbazone, and m.p. oxime given): I (R = R3 = H, R1 = CHO, R2 = Br), 118-20鎺?13, -, 221鎺? 104鎺? I (R = R1 = CHO, R2 = Br, R3 = H), 158-60鎺?13, 117-18鎺? -, -. I [R = R2 = R3 = H, R1 = CH(OEt)2] is treated with 0.13 mole BuLi and a solution of 12 g. Br is added to give 5 g. I (R = Br, R1 = CHO, R2 = R3 = H), m. 34鎺?(hexane); thiosemicarbazone m. 235鎺? oxime m. 86鎺? Similarly prepared are the following I (R2 = H) (R, R1, R3, b.p./mm., m.p., m.p. thiosemicarbazone, and m.p. oxime given): H, CHO, Br, 114-16鎺?17-18, -, 180鎺? 91鎺? Br, CHO, Br, 122-35鎺?12-14, 45-6鎺?(ligroine), 266鎺? 136鎺? The following I (R1 = H) are prepared according to known methods (R, R2, R3, b.p./mm., m.p., m.p. thiosemicarbazone, and m.p. oxime given): CHO, Br, H, -, 45-6鎺? 216鎺? 174鎺? CHO, H, Br, 112-14鎺?14, -, 173-4鎺? 152-4鎺? A mixture of 0.01 mole 0-HOC6H4Ac, 0.01 mole III, 1 ml. 5N NaOH, and 10 ml. EtOH is heated 2 hrs. at 60鎺?to give 10% 0-hydroxyphenyl 2-(3-bromo-2-thienyl)vinyl ketone, m. 124鎺? Similarly prepared are the following II (R = R2 = H, R1 = Br) (Ar, m.p., and % yield given): 0-HOC6H4, 108鎺? 11; 2,5-HO(O2N)C6H3, 195鎺? 65. A mixture of 0.01 mole 5-bromo-2-acetylthiophene, 0.01 mole 2-formylthiophene, 3.2 ml. N NaOH, and 20 ml. EtOH is refrigerated 2 hrs. to give 20% II (R = R1 = R2 = H, Ar + 5-bromo-2-thienyl), m. 113鎺? Similarly prepared are the following II (R2 = H) (Ar, R, R1, m.p., and % yield given): 5-bromo-2-thienyl, H, Br, 135鎺? 33; 5-bromo-2-thienyl, Br, H, 144鎺? 40; 2-thienyl, Br, H, 100鎺? 60; 2-pyridyl, Br, H, 145鎺? 80; 2-pyridyl, H, Br, 136鎺? 70. 3-Bromo-2-cyanothiophene (m. 50鎺? and the following I are prepared according to the P. Reynaud-R. Delaby method for the preparation of 2-cyanothiophene (R, R1, R2, R3, b.p./mm., and m.p. given): CN, H, Br, H, -, 45鎺?(ether-ligroine); CN, H, H, Br, 124鎺?34, -; Br, CN, H, H, 130鎺?22, -; H, CN, Br, H, -, 56 (ether-ligroine); H, CN, H, Br, -, 33鎺?(aqueous alc.); Br, CN, H, Br, -, 76鎺?(aqueous alc.). The bromocyanothiophenes (0.01 mole) are treated with 10 ml. H2O2 at 50鎺?in the presence of 4 ml. 25% KOH to give 4-bromo-2-thiophenecarboxamide, m. 153-4鎺? and the following I (R, R1, R2, R3, and m.p. given): CONH2, H, H, Br, 164鎺? Br, CONH2, H, H, 142鎺? H, CONH2, Br, H, 146鎺? H, CONH2, H, Br, 146鎺? Br, CONH2, H, Br, 140-1鎺? CONH2, Br, H, H, 103鎺? 5-Bromo-3-formylthiophene (0.005 mole) is treated with 800 mg. KMnO4 to give 0.6 g. 5-bromo-3-thiophenecarboxylic acid, m. 139鎺?(aqueous alc.). Similarly prepared are the following I (R, R1, R2, R3, and m.p. given): CO2H, Br, H, H, 197-8鎺? CO2H, H, Br, H, 123鎺? CO2H, H, H, Br, 142鎺? Br, CO2H, H, H, 180鎺? H, CO2H, Br, H, 159鎺? H, CO2H, H, Br, 139鎺? Br, CO2H, H, Br, 178鎺? N.M.R. data are given. In the experiment, the researchers used many compounds, for example, 5-Bromothiophene-3-carbaldehyde (cas: 18791-79-2Category: bromides-buliding-blocks).

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Nambo, Masakazu et al. published their research in ACS Catalysis in 2022 | CAS: 18791-79-2

5-Bromothiophene-3-carbaldehyde (cas: 18791-79-2) belongs to organobromine compounds. A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. Organobromine compounds have fallen under increased scrutiny for their environmental impact. The reactivity of organobromine compounds resembles but is intermediate between the reactivity of organochlorine and organoiodine compounds. For many applications, organobromides represent a compromise of reactivity and cost.HPLC of Formula: 18791-79-2

Desulfonylative Coupling of Alkylsulfones with gem-Difluoroalkenes by Visible-Light Photoredox Catalysis was written by Nambo, Masakazu;Ghosh, Koushik;Yim, Jacky C.-H.;Tahara, Yasuyo;Inai, Naoto;Yanai, Takeshi;Crudden, Cathleen M.. And the article was included in ACS Catalysis in 2022.HPLC of Formula: 18791-79-2 This article mentions the following:

The desulfonylative radical addition of tertiary alkyl groups I [R¹ = 2-phenylethyl, 1,3-dioxolan-2-ylmethyl, prop-2-en-1-yl, etc. R² = Me, 3-chloropropyl, 2-(tert-butoxy)-2-oxoethyl, etc.; R¹ = R² = -(CH₂)₅-, -(CH₂)₂O(CH₂)₂-, 2,3-dihydro-1H-inden-2-ylidene; R³ = H, Me] to gem-difluoroalkenes F₂C=CHR⁴ (R⁴ = 4-(4-chlorophenyl)phenyl, naphthalen-2-yl, 1-benzothiophen-3-yl, etc.) by photoredox Ir-catalyst was described. This method exhibits broad substrate scope, affording structurally diverse (E)-fluoroalkene derivatives (R¹)(R²)R³CC(F)=CHR⁴ in a highly stereoselective manner. The resulting (E)-fluoroalkenes were converted into complex fused cyclic compounds e.g., II by intramol. cyclization reactions. Control experiments and theor. calculations are consistent with a single Ir catalyst playing the dual role of generating radical species from sulfones via single electron transfer and mediating Z/E isomerization via energy transfer. A subset of fluoroalkenes provided Z stereoisomers with <90% selectivity, but the same alkenes could also be obtained as E isomers (R¹)(R²)R³CC(F)=CHR⁴ (R¹ = 2-phenylethyl, R² = R³ = Me, R⁴ = m-OMe, m-Br, p-Me.) with high selectivity by taking advantage of a secondary Z to E photoisomerization. In the experiment, the researchers used many compounds, for example, 5-Bromothiophene-3-carbaldehyde (cas: 18791-79-2HPLC of Formula: 18791-79-2).

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Xia, Anjie et al. published their research in Organic Letters in 2019 | CAS: 18791-79-2

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Gao, Li-Bin et al. published their research in Heteroatom Chemistry in 2016 | CAS: 18791-79-2

5-Bromothiophene-3-carbaldehyde (cas: 18791-79-2) belongs to organobromine compounds. Bromine is more electronegative than carbon (2.9 vs 2.5). Consequently, the carbon in a carbon閳ユ彽romine bond is electrophilic, i.e. alkyl bromides are alkylating agents. Commercially available organobromine pharmaceuticals include the vasodilator nicergoline, the sedative brotizolam, the anticancer agent pipobroman, and the antiseptic merbromin. SDS of cas: 18791-79-2

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Eras, J. et al. published their research in Journal of Heterocyclic Chemistry in 1984 | CAS: 18791-79-2

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Cheng, Huicheng et al. published their research in Tetrahedron Letters in 2013 | CAS: 18791-79-2

5-Bromothiophene-3-carbaldehyde (cas: 18791-79-2) belongs to organobromine compounds. Bromine is more electronegative than carbon (2.9 vs 2.5). Consequently, the carbon in a carbon–bromine bond is electrophilic, i.e. alkyl bromides are alkylating agents. Many of the alkyl bromine derivatives are excellent alkylating agents since bromides are good leaving groups. Tribromides, like tetrabutylammonium tribromide, are used as a solid source of bromine. N-bromosuccimide (NBS) is used for the selective bromination of allylic bonds.Name: 5-Bromothiophene-3-carbaldehyde

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary