Category: 1779-49-3

In 2019,Journal of the American Chemical Society included an article by Liu, Wen-Qiang; Lei, Tao; Zhou, Shuai; Yang, Xiu-Long; Li, Jian; Chen, Bin; Sivaguru, Jayaraman; Tung, Chen-Ho; Wu, Li-Zhu. Application In Synthesis of Methyltriphenylphosphonium bromide. The article was titled 《Cobaloxime Catalysis: Selective Synthesis of Alkenylphosphine Oxides under Visible Light》. The information in the text is summarized as follows:

Direct activation of H-phosphine oxide to react with an unsaturated C-C bond is a straightforward approach for accessing alkenylphosphine oxides, which shows significant applications in both synthetic and material fields. However, expensive metals and strong oxidants are typically required to realize the transformation. Here, the authors demonstrate the utility of earth-abundant cobaloxime to convert H-phosphine oxide into its reactive radical species under visible light irradiation The radical species thus generated can be used to functionalize alkenes and alkynes without any external photosensitizer and oxidant. The coupling with terminal alkene generates E-alkenylphosphine oxide with excellent chemo- and stereoselectivity. The reaction with terminal alkyne yields linear E-alkenylphosphine oxide via neutral radical addition, while addition with internal ones generates cyclic benzophosphine oxides and H. Mechanistic studies on radical trapping experiments, ESR studies, and spectroscopic measurements confirm the formation of phosphinoyl radical and Co intermediates that are from capturing the electron and proton eliminated from H-phosphine oxide. The highlight of the authors’ mechanistic study is the dual role played by cobaloxime, viz., both as the visible light absorber to activate the P(O)-H bond as well as a H transfer agent to influence the reaction pathway. This synergetic feature of the cobaloxime catalyst preforming multiple functions under ambient condition provides a convergent synthetic approach to vinylphosphine oxides directly from H-phosphine oxides and alkenes (or alkynes). After reading the article, we found that the author used Methyltriphenylphosphonium bromide(cas: 1779-49-3Application In Synthesis of Methyltriphenylphosphonium bromide)

Methyltriphenylphosphonium bromide(cas: 1779-49-3) is used for methylenation through the Wittig reaction. It is utilized in the synthesis of an enyne and 9-isopropenyl -phenanthrene by using sodium amide as reagent. Application In Synthesis of Methyltriphenylphosphonium bromide

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Quality Control of Methyltriphenylphosphonium bromideIn 2021 ,《Asymmetric Total Synthesis of Dankasterones A and B and Periconiastone A Through Radical Cyclization》 appeared in Angewandte Chemie, International Edition. The author of the article were Chen, Pengquan; Wang, Cheng; Yang, Rui; Xu, Hongjin; Wu, Jinghua; Jiang, Huanfeng; Chen, Kai; Ma, Zhiqiang. The article conveys some information:

We describe herein the assembly of the cis-decalin framework through radical cyclization initiated by metal-catalyzed hydrogen atom transfer (MHAT), further applied it in the asym. synthesis of dankasterones A and B and periconiastone A. Position-selective C-H oxygenation allowed for installation of the necessary functionality. A radical rearrangement was adopted to create 13(14→8)abeo-8-ergostane skeleton. Interconversion of dankasterone B and periconiastone A was realized through biomimetic intramol. aldol and retro-aldol reactions. The MHAT-based approach, serves as a new dissection means, is complementary to the conventional ways to establish cis-decalin framework. In the experiment, the researchers used many compounds, for example, Methyltriphenylphosphonium bromide(cas: 1779-49-3Quality Control of Methyltriphenylphosphonium bromide)

Methyltriphenylphosphonium bromide(cas: 1779-49-3) is a lipophilic molecule with a cation allowing for it to be used to deliver molecules to specific cell components. Also considered an antineoplastic agent.Quality Control of Methyltriphenylphosphonium bromide

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

In 2019,Journal of the American Chemical Society included an article by Chen, Xiao-Wang; Zhu, Lei; Gui, Yong-Yuan; Jing, Ke; Jiang, Yuan-Xu; Bo, Zhi-Yu; Lan, Yu; Li, Jing; Yu, Da-Gang. Quality Control of Methyltriphenylphosphonium bromide. The article was titled 《Highly Selective and Catalytic Generation of Acyclic Quaternary Carbon Stereocenters via Functionalization of 1,3-Dienes with CO2》. The information in the text is summarized as follows:

A highly selective copper-catalyzed generation of chiral all-carbon acyclic quaternary stereocenters via functionalization of 1,3-dienes with CO2 is reported. A variety of readily available 1,1-disubstituted 1,3-dienes, as well as a 1,3,5-triene, undergo reductive hydroxymethylation with high chemo-, regio-, E/Z-, and enantioselectivities. The reported method features good functional group tolerance, is readily scaled up to at least 5 mmol of starting diene, and generates chiral products that are useful building blocks for further derivatization. Systemic mechanistic investigations using d. functional theory calculations were performed and provided the first theor. investigation for an asym. transformation involving CO2. These computational results indicate that the 1,2-hydrocupration of 1,3-diene proceeds with high π-facial selectivity to generate an (S)-allylcopper intermediate, which further induces the chirality of the quaternary carbon center in the final product. The 1,4-addition of an internal allylcopper complex, which differs from previous reports involving terminal allylmetallic intermediates, to CO2 kinetically determines the E/Z- and regioselectivity. The rapid reduction of a copper carboxylate intermediate to the corresponding silyl-ether in the presence of Me(MeO)2SiH provides the exergonic impetus and leads to chemoselective hydroxymethylation rather than carboxylation. These results provide new insights for guiding further development of asym. C-C bond formations with CO2. After reading the article, we found that the author used Methyltriphenylphosphonium bromide(cas: 1779-49-3Quality Control of Methyltriphenylphosphonium bromide)

Methyltriphenylphosphonium bromide(cas: 1779-49-3) is an organophosphorus compound, with potential use as a precursor and a solvent in organic synthesis. And it is used widely for methylenation via the Wittig reaction.Quality Control of Methyltriphenylphosphonium bromide

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

The author of 《Intermolecular 1,4-Carboamination of Conjugated Dienes Enabled by Cp*RhIII-Catalyzed C-H Activation》 were Pinkert, Tobias; Wegner, Tristan; Mondal, Shobhan; Glorius, Frank. And the article was published in Angewandte Chemie, International Edition in 2019. Electric Literature of C19H18BrP The author mentioned the following in the article:

A protocol for the three-component 1,4-carboamination of dienes is described. Synthetically versatile Weinreb amides were coupled with 1,3-dienes and readily available dioxazolones as the nitrogen source using [Cp*RhCl2]2-catalyzed C-H activation to deliver the 1,4-carboaminated products. This transformation proceeds under mild reaction conditions and affords the products with high levels of regio- and E-selectivity. Mechanistic investigations suggest an intermediate RhIII-allyl species is trapped by an electrophilic amidation reagent in a redox-neutral fashion. The experimental part of the paper was very detailed, including the reaction process of Methyltriphenylphosphonium bromide(cas: 1779-49-3Electric Literature of C19H18BrP)

Methyltriphenylphosphonium bromide(cas: 1779-49-3) is an organophosphorus compound, with potential use as a precursor and a solvent in organic synthesis. And it is used widely for methylenation via the Wittig reaction.Electric Literature of C19H18BrP

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

In 2019,Angewandte Chemie, International Edition included an article by Meng, Qing-Yuan; Schirmer, Tobias E.; Katou, Kousuke; Koenig, Burkhard. Recommanded Product: 1779-49-3. The article was titled 《Controllable Isomerization of Alkenes by Dual Visible-Light-Cobalt Catalysis》. The information in the text is summarized as follows:

Thermodn. and kinetic isomerization of alkenes accomplished by the combination of visible light with Co catalysis is reported. Utilizing Xantphos as the ligand, the most stable isomers are obtained, while isomerizing terminal alkenes over one position can be selectively controlled by using DPEphos as the ligand. The presence of the donor-acceptor dye 4CzIPN accelerates the reaction further. Transformation of exocyclic alkenes into the corresponding endocyclic products could be efficiently realized by using 4CzIPN and Co(acac)2 in the absence of any addnl. ligands. Spectroscopic and spectroelectrochem. investigations indicate CoI being involved in the generation of a Co hydride, which subsequently adds to alkenes initiating the isomerization. After reading the article, we found that the author used Methyltriphenylphosphonium bromide(cas: 1779-49-3Recommanded Product: 1779-49-3)

Methyltriphenylphosphonium bromide(cas: 1779-49-3) is used for methylenation through the Wittig reaction. It is utilized in the synthesis of an enyne and 9-isopropenyl -phenanthrene by using sodium amide as reagent. Recommanded Product: 1779-49-3

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

《Synthesis of All-Carbon Quaternary Centers by Palladium-Catalyzed Olefin Dicarbofunctionalization》 was published in Angewandte Chemie, International Edition in 2020. These research results belong to Koy, Maximilian; Bellotti, Peter; Katzenburg, Felix; Daniliuc, Constantin G.; Glorius, Frank. Reference of Methyltriphenylphosphonium bromide The article mentions the following:

The redox-neutral dicarbofunctionalization of tri- and tetrasubstituted olefins to form a variety of (hetero)cyclic compounds under photoinduced palladium catalysis is described. This cascade reaction process was used to couple styrenes or acryl amides with a broad range of highly decorated olefins tethered to aryl or alkyl bromides (>50 examples). This procedure enables one or two contiguous all-carbon quaternary centers to be formed in a single step. The products could be readily diversified and applied in the synthesis of a bioactive oxindole analog. The experimental part of the paper was very detailed, including the reaction process of Methyltriphenylphosphonium bromide(cas: 1779-49-3Reference of Methyltriphenylphosphonium bromide)

Methyltriphenylphosphonium bromide(cas: 1779-49-3) is used for methylenation through the Wittig reaction. It is utilized in the synthesis of an enyne and 9-isopropenyl -phenanthrene by using sodium amide as reagent. Reference of Methyltriphenylphosphonium bromide

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

《Cooperative NHC and Photoredox Catalysis for the Synthesis of β-Trifluoromethylated Alkyl Aryl Ketones》 was written by Meng, Qing-Yuan; Doeben, Nadine; Studer, Armido. HPLC of Formula: 1779-49-3This research focused ontrifluoromethyl alkyl aryl ketone preparation; cooperative photoredox catalyzed trifluoromethylation styrene acid fluoride; NHC catalysis; trifluoromethylation; visible light catalysis. The article conveys some information:

Despite the great potential of radical chem. in organic synthesis, N-heterocyclic carbene (NHC)-catalyzed reactions involving radical intermediates are not well explored. This communication reports the three-component coupling of aroyl fluorides, styrenes and the Langlois reagent (CF3SO2Na) to give various β-trifluoromethylated alkyl aryl ketones with good functional group tolerance in moderate to high yields by cooperative photoredox/NHC catalysis. The alkene acyltrifluoromethylation proceeds via radical/radical cross coupling of ketyl radicals with benzylic C-radicals. The ketyl radicals are generated via SET reduction of in situ formed acylazolium ions whereas the benzylic radicals derive from trifluoromethyl radical addition onto styrenes. In addition to this study using Methyltriphenylphosphonium bromide, there are many other studies that have used Methyltriphenylphosphonium bromide(cas: 1779-49-3HPLC of Formula: 1779-49-3) was used in this study.

Methyltriphenylphosphonium bromide(cas: 1779-49-3) is a lipophilic molecule with a cation allowing for it to be used to deliver molecules to specific cell components. Also considered an antineoplastic agent.HPLC of Formula: 1779-49-3

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

《Extractive desulfurization of fuels using diglycol based deep eutectic solvents》 was published in Journal of Environmental Chemical Engineering in 2020. These research results belong to Jha, Divyam; Haider, Mohd Belal; Kumar, Rakesh; Balathanigaimani, Marriyappan Sivagnanam. Formula: C19H18BrP The article mentions the following:

In this work, the effect of Deep Eutectic Solvents (DESs) on sulfur extraction of organo-sulfur compounds was investigated. Different DESs were prepared using a common hydrogen bond donor, Diglycol, and different hydrogen bond acceptors. The effects of experiment variables such as temperature, DESs/feed ratio, and the time on desulfurization efficiency of different organo-sulfur compounds were also studied. Results show that Tetra Bu ammonium bromide based DES showed relatively higher sulfur removal capabilities (Dibenzothiophene (DBT): -92%, 2- Methylthiophene (2-MT): -86% and Thiophene (T): -71%) as compared to other DESs. Also, all DESs have higher DBT extraction efficiency followed by 2-MT and T. Further, non-random two liquids (NRTL) thermodn. model was employed to model liquid-liquid equilibrium The experimental part of the paper was very detailed, including the reaction process of Methyltriphenylphosphonium bromide(cas: 1779-49-3Formula: C19H18BrP)

Methyltriphenylphosphonium bromide(cas: 1779-49-3) is an organophosphorus compound, with potential use as a precursor and a solvent in organic synthesis. And it is used widely for methylenation via the Wittig reaction.Formula: C19H18BrP

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

《Trifluorinated Tetralins via I(I)/I(III)-Catalysed Ring Expansion: Programming Conformation by [CH2CH2] → [CF2CHF] Isosterism》 was written by Neufeld, Jessica; Stuenkel, Timo; Mueck-Lichtenfeld, Christian; Daniliuc, Constantin G.; Gilmour, Ryan. HPLC of Formula: 1779-49-3This research focused ontrifluorinated tetralin synthesis iodine catalyzed ring expansion fluorinated methyleneindane; fluorination; iodine(III); organocatalysis; ring expansion; tetralin. The article conveys some information:

Saturated, fluorinated carbocycles are emerging as important modules for contemporary drug discovery. To expand the current portfolio, the synthesis of novel trifluorinated tetralins has been achieved. Fluorinated methyleneindanes serve as convenient precursors and undergo efficient difluorinative ring expansion with in situ generated p-TolIF2 (>20 examples, up to >95%). A range of diverse substituents are tolerated under standard catalysis conditions and this is interrogated by Hammett anal. X-ray anal. indicates a preference for the CH-F bond to occupy a pseudo-axial orientation, consistent with stabilizing σC-H→σC-F* interactions. The replacement of the sym. [CH2-CH2] motif by [CF2-CHF] removes the conformational degeneracy intrinsic to the parent tetralin scaffold leading to a predictable half-chair. The conformational behavior of this novel structural balance has been investigated by computational anal. and is consistent with stereoelectronic theory. In addition to this study using Methyltriphenylphosphonium bromide, there are many other studies that have used Methyltriphenylphosphonium bromide(cas: 1779-49-3HPLC of Formula: 1779-49-3) was used in this study.

Methyltriphenylphosphonium bromide(cas: 1779-49-3) is a lipophilic molecule with a cation allowing for it to be used to deliver molecules to specific cell components. Also considered an antineoplastic agent.HPLC of Formula: 1779-49-3

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

The author of 《Liquid-Liquid Equilibrium Measurements for the Extraction of Pyridine and Benzothiazole from n-Alkanes Using Deep Eutectic Solvents》 were Warrag, Samah E. E.; Alli, Ruth D.; Kroon, Maaike C.. And the article was published in Journal of Chemical & Engineering Data in 2019. COA of Formula: C19H18BrP The author mentioned the following in the article:

The liquid-liquid extraction of a nitrogen-containing aromatic “”pyridine”” and nitrogen/sulfur-containing aromatic “”benzothiazole”” from n-hexane and n-heptane using deep eutectic solvents (DESs) was studied in this work. A DES composed of methyltriphenylphosphonium bromide as hydrogen bond acceptor and ethylene glycol as hydrogen bond donor was selected for this separation The main objective of this work was to assess whether the same DES can be applied for the denitrogenation “”extraction of pyridine”” and desulfurization “”extraction of benzothiazole”” of fuels. Moreover, the influence of n-alkane chain length on the extraction performance was studied. First, the solubilities of the pyridine, benzothiazole, n-hexane, and n-heptane in the DES were determined at 298.2 K and 1.01 bar. Thereafter, the pseudoternary liquid-liquid equilibrium (LLE) data for the four systems {n-hexane + pyridine + DES}, {n-heptane + pyridine + DES}, {n-hexane + benzothiazole + DES}, and {n-heptane + benzothiazole + DES} were determined at a temperature of 298.2 K and a pressure of 1.01 bar. The assumption of a pseudoternary system was validated showing that none of the DES’ constituents appears in the raffinate phase. From the LLE data the distribution ratios and selectivites of pyridine and benzothiazole were calculated Both pyridine and benzothiazole were successfully extracted from their mixtures with n-hexane and n-heptane, with pyridine showing higher selectivity than benzothiazole and almost similar distribution ratios. Finally, The LLE data were correlated with the nonrandom two-liquid model using ASPEN PLUS. The modeled results showed a strong correlation with the exptl. results (relative mean standard deviation (%)) = 0.04-0.36. After reading the article, we found that the author used Methyltriphenylphosphonium bromide(cas: 1779-49-3COA of Formula: C19H18BrP)

Methyltriphenylphosphonium bromide(cas: 1779-49-3) is a lipophilic molecule with a cation allowing for it to be used to deliver molecules to specific cell components. Also considered an antineoplastic agent.COA of Formula: C19H18BrP

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary