Category: 1779-49-3

《Iron-Catalyzed Tunable and Site-Selective Olefin Transposition》 was published in Journal of the American Chemical Society in 2020. These research results belong to Yu, Xiaolong; Zhao, Haonan; Li, Ping; Koh, Ming Joo. Related Products of 1779-49-3 The article mentions the following:

The catalytic isomerization of C-C double bonds is an indispensable chem. transformation used to deliver higher-value analogs and has important utility in the chem. industry. Notwithstanding the advances reported in this field, there is compelling demand for a general catalytic solution that enables precise control of the C=C bond migration position, in both cyclic and acyclic systems, to furnish disubstituted and trisubstituted alkenes. Here, we show that catalytic amounts of an appropriate earth-abundant iron-based complex, a base and a boryl compound, promote efficient and controllable alkene transposition. Mechanistic investigations reveal that these processes likely involve in situ formation of an iron-hydride species which promotes olefin isomerization through sequential olefin insertion/β-hydride elimination. Through this strategy, regiodivergent access to different products from one substrate can be facilitated, isomeric olefin mixtures commonly found in petroleum-derived feedstock can be transformed to a single alkene product, and unsaturated moieties embedded within linear and heterocyclic biol. active entities can be obtained. In the experiment, the researchers used many compounds, for example, Methyltriphenylphosphonium bromide(cas: 1779-49-3Related Products of 1779-49-3)

Methyltriphenylphosphonium bromide(cas: 1779-49-3) is used for methylenation through the Wittig reaction. It is utilized in the synthesis of an enyne and 9-isopropenyl -phenanthrene by using sodium amide as reagent. Related Products of 1779-49-3

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

《Cobalt(II)-Catalyzed Stereoselective Olefin Isomerization: Facile Access to Acyclic Trisubstituted Alkenes》 was published in Journal of the American Chemical Society in 2020. These research results belong to Zhang, Sheng; Bedi, Deepika; Cheng, Lu; Unruh, Daniel K.; Li, Guigen; Findlater, Michael. SDS of cas: 1779-49-3 The article mentions the following:

Stereoselective synthesis of trisubstituted alkenes is a long-standing challenge in organic chem., due to the small energy differences between E and Z isomers of trisubstituted alkenes (compared with 1,2-disubstituted alkenes). Transition metal-catalyzed isomerization of 1,1-disubstituted alkenes can serve as an alternative approach to trisubstituted alkenes, but it remains underdeveloped owing to issues relating to reaction efficiency and stereoselectivity. Here we show that a novel cobalt catalyst can overcome these challenges to provide an efficient and stereoselective access to a broad range of trisubstituted alkenes. This protocol is compatible with both mono- and dienes and exhibits a good functional group tolerance and scalability. Moreover, it has proven to be a useful tool to construct organic luminophores and a deuterated trisubstituted alkene. A preliminary study of the mechanism suggests that a cobalt-hydride pathway is involved in the reaction. The high stereoselectivity of the reaction is attributed to both a π-π stacking effect and the steric hindrance between substrate and catalyst. After reading the article, we found that the author used Methyltriphenylphosphonium bromide(cas: 1779-49-3SDS of cas: 1779-49-3)

Methyltriphenylphosphonium bromide(cas: 1779-49-3) is an organophosphorus compound, with potential use as a precursor and a solvent in organic synthesis. And it is used widely for methylenation via the Wittig reaction.SDS of cas: 1779-49-3

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

《Catalyzing the Hydrodefluorination of CF3-Substituted Alkenes by PhSiH3. H• Transfer from a Nickel Hydride》 was written by Yao, Chengbo; Wang, Shuai; Norton, Jack; Hammond, Matthew. Recommanded Product: 1779-49-3 And the article was included in Journal of the American Chemical Society in 2020. The article conveys some information:

The hydrodefluorination of CF3-substituted alkenes can be catalyzed by a nickel(II) hydride bearing a pincer ligand. The catalyst loading can be as low as 1 mol%. Gem-Difluoroalkenes containing a number of functional groups can be formed in good to excellent yields by a radical mechanism initiated by H• transfer from the nickel hydride. The relative reactivity of various substrates supports the proposed mechanism, as does a TEMPO trapping experiment In the experiment, the researchers used many compounds, for example, Methyltriphenylphosphonium bromide(cas: 1779-49-3Recommanded Product: 1779-49-3)

Methyltriphenylphosphonium bromide(cas: 1779-49-3) is an organophosphorus compound, with potential use as a precursor and a solvent in organic synthesis. And it is used widely for methylenation via the Wittig reaction.Recommanded Product: 1779-49-3

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

In 2019,Journal of the American Chemical Society included an article by Zhou, Shupeng; Xia, Kaifu; Leng, Xuebing; Li, Ang. Synthetic Route of C19H18BrP. The article was titled 《Asymmetric Total Synthesis of Arcutinidine, Arcutinine, and Arcutine》. The information in the text is summarized as follows:

We have accomplished the asym. total synthesis of arcutinidine, arcutinine, and arcutine, three arcutine type C20-diterpenoid alkaloids. A pentacyclic intermediate was rapidly assembled by using two Diels-Alder reactions. We developed a cascade sequence of Prins cyclization and Wagner-Meerwein rearrangement to construct the core of arcutinidine, which was then elaborated into an oxygenated pentacycle through a scalable route. Chemoselective reductive amination followed by spontaneous imine formation furnished the pyrroline motif at a final stage. We clarified the S configuration of the α-carbon of the acyl group within arcutine through chem. synthesis and crystallog. anal. In the part of experimental materials, we found many familiar compounds, such as Methyltriphenylphosphonium bromide(cas: 1779-49-3Synthetic Route of C19H18BrP)

Methyltriphenylphosphonium bromide(cas: 1779-49-3) is used for methylenation through the Wittig reaction. It is utilized in the synthesis of an enyne and 9-isopropenyl -phenanthrene by using sodium amide as reagent. Synthetic Route of C19H18BrP

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

The author of 《Copper-Catalyzed 1,2-Methoxy Methoxycarbonylation of Alkenes with Methyl Formate》 were Budai, Balazs; Leclair, Alexandre; Wang, Qian; Zhu, Jieping. And the article was published in Angewandte Chemie, International Edition in 2019. Formula: C19H18BrP The author mentioned the following in the article:

Reported here is a copper-catalyzed 1,2-methoxy methoxycarbonylation of alkenes by an unprecedented use of Me formate as a source of both the methoxy and the methoxycarbonyl groups. This reaction transforms styrene and its derivatives into value-added β-methoxy alkanoates and cinnamates, as well as medicinally important five-membered heterocycles, such as functionalized tetrahydrofurans, γ-lactones, and pyrrolidines. These findings suggest that pre-coordination of electron-rich alkenes to copper might play an important role in accelerating the addition of nucleophilic radicals to electron-rich alkenes, and could have general implications in the design of novel radical-based transformations.Methyltriphenylphosphonium bromide(cas: 1779-49-3Formula: C19H18BrP) was used in this study.

Methyltriphenylphosphonium bromide(cas: 1779-49-3) is a lipophilic molecule with a cation allowing for it to be used to deliver molecules to specific cell components. Also considered an antineoplastic agent.Formula: C19H18BrP

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

《Harnessing Applied Potential: Selective β-Hydrocarboxylation of Substituted Olefins》 was published in Journal of the American Chemical Society in 2020. These research results belong to Alkayal, Anas; Tabas, Volodymyr; Montanaro, Stephanie; Wright, Iain A.; Malkov, Andrei V.; Buckley, Benjamin R.. Safety of Methyltriphenylphosphonium bromide The article mentions the following:

The construction of carboxylic acid compounds in a selective fashion from low value materials such as alkenes remains a long-standing challenge to synthetic chemists. In particular, β-addition to styrenes is underdeveloped. Herein we report a new electrosynthetic approach to the selective hydrocarboxylation of alkenes that overcomes the limitations of current transition metal and photochem. approaches. The reported method allows unprecedented direct access to carboxylic acids derived from β,β-trisubstituted alkenes, in a highly regioselective manner.Methyltriphenylphosphonium bromide(cas: 1779-49-3Safety of Methyltriphenylphosphonium bromide) was used in this study.

Methyltriphenylphosphonium bromide(cas: 1779-49-3) is an organophosphorus compound, with potential use as a precursor and a solvent in organic synthesis. And it is used widely for methylenation via the Wittig reaction.Safety of Methyltriphenylphosphonium bromide

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

《Asymmetric Total Synthesis of (+)-Waihoensene》 was published in Journal of the American Chemical Society in 2020. These research results belong to Qu, Yongzheng; Wang, Zheyuan; Zhang, Zhongchao; Zhang, Wendou; Huang, Jun; Yang, Zhen. Category: bromides-buliding-blocks The article mentions the following:

The asym. total synthesis of (+)-waihoensene (I), which has a cis-fused [6,5,5,5] tetracyclic core bearing an angular triquinane, a cis-fused six-membered ring, and four contiguous quaternary carbon atoms, was achieved through a sequence of chem. reactions in a stereochem. well-defined manner. The total synthesis features the following: (1) Cu-catalyzed asym. conjugated 1,4-addition; (2) diastereoselective Conia-ene type reaction; (3) diastereoselective intramol. Pauson-Khand reaction; (4) Ni-catalyzed diastereoselective conjugated 1,4-addition; and (5) radical-initiated intramol. hydrogen atom transfer (HAT). Control experiments and d. functional theory calculations support the proposed HAT process.Methyltriphenylphosphonium bromide(cas: 1779-49-3Category: bromides-buliding-blocks) was used in this study.

Methyltriphenylphosphonium bromide(cas: 1779-49-3) is used for methylenation through the Wittig reaction. It is utilized in the synthesis of an enyne and 9-isopropenyl -phenanthrene by using sodium amide as reagent. Category: bromides-buliding-blocks

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Recommanded Product: 1779-49-3In 2019 ,《Chiral Bronsted Acid Catalyzed Dynamic Kinetic Asymmetric Hydroamination of Racemic Allenes and Asymmetric Hydroamination of Dienes》 appeared in Angewandte Chemie, International Edition. The author of the article were Lin, Jin-Shun; Li, Tao-Tao; Jiao, Guan-Yuan; Gu, Qiang-Shuai; Cheng, Jiang-Tao; Lv, Ling; Liu, Xin-Yuan. The article conveys some information:

The first highly efficient and practical chiral Bronsted acid catalyzed dynamic kinetic asym. hydroamination (DyKAH) of racemic allenes and asym. hydroamination of unactivated dienes with both high E/Z selectivity and enantioselectivity are described herein. The transformation proceeds through a new catalytic asym. model involving a highly reactive π-allylic carbocationic intermediate, generated from racemic allenes or dienes through a proton transfer mediated by an activating/directing thiourea group. This method affords expedient access to structurally diverse enantioenriched, potentially bioactive alkenyl-containing aza-heterocycles and bicyclic aza-heterocycles. In the part of experimental materials, we found many familiar compounds, such as Methyltriphenylphosphonium bromide(cas: 1779-49-3Recommanded Product: 1779-49-3)

Methyltriphenylphosphonium bromide(cas: 1779-49-3) is a lipophilic molecule with a cation allowing for it to be used to deliver molecules to specific cell components. Also considered an antineoplastic agent.Recommanded Product: 1779-49-3

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Application In Synthesis of Methyltriphenylphosphonium bromideIn 2019 ,《Regio- and Enantioselective C-H Cyclization of Pyridines with Alkenes Enabled by a Nickel/N-Heterocyclic Carbene Catalysis》 appeared in Journal of the American Chemical Society. The author of the article were Zhang, Wu-Bin; Yang, Xin-Tuo; Ma, Jun-Bao; Su, Zhi-Ming; Shi, Shi-Liang. The article conveys some information:

Annulated pyridines are ubiquitous scaffolds in many bioactive mols. A highly regio- and enantioselective Ni(0)-catalyzed endo-selective C-H cyclization of pyridines with alkenes was developed. An unprecedented enantioselective C-H activation at pyridyl 3- or 4-positions was enabled by bulky chiral N-heterocyclic carbene ligands. This protocol provides expedient access to a series of optically active 5,6,7,8-tetrahydroquinolines and 5,6,7,8-tetrahydroisoquinolines, compounds otherwise accessed with difficulty, in moderate to high yields (up to 99% yield) and enantioselectivities (up to 99% ee). To the authors’ knowledge, this is the first example of enantioselective C-H cyclization of pyridines to chiral annulated products.Methyltriphenylphosphonium bromide(cas: 1779-49-3Application In Synthesis of Methyltriphenylphosphonium bromide) was used in this study.

Methyltriphenylphosphonium bromide(cas: 1779-49-3) is a lipophilic molecule with a cation allowing for it to be used to deliver molecules to specific cell components. Also considered an antineoplastic agent.Application In Synthesis of Methyltriphenylphosphonium bromide

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

《1,3-Adamantanedicarboxylate and 1,3-Adamantanediacetate as Uranyl Ion Linkers: Effect of Counterions, Solvents and Differences in Flexibility》 was written by Thuery, Pierre; Atoini, Youssef; Harrowfield, Jack. Electric Literature of C19H18BrPThis research focused onuranyl adamantanediacetate adamantanedicarboxylate coordination polymer preparation crystal structure; photoluminescence luminescence uranyl adamantanediacetate adamantanedicarboxylate coordination polymer. The article conveys some information:

Seven homo- or heterometallic uranyl ion complexes with 1,3-adamantanedicarboxylic acid (H2ADC) or 1,3-adamantanediacetic acid (H2ADA) have been synthesized under solvo-hydrothermal conditions in the presence of different counterions and organic cosolvents, and characterized by their crystal structure and uranyl emission spectrum. [PPh3Me][UO2(ADC)(NO3)] (1) crystallizes as a simple monoperiodic chain, but [PPh4]2[(UO2)2(ADC)3]·2H2O (2) and [PPh4]2[(UO2)2(ADA)3] (3) display trough-like monoperiodic polymers (assembled in pairs in 3) in the cavity of which the counterions are located. A similar arrangement is found in [Ni(cyclen)(H2O)][(UO2)2(ADC)3]·H2O (4). Diaxial bonding of NiII in [(UO2)2(ADC)2Ni(R,S-Me6cyclam)(HCOO)2]·CH3CN (5) and [UO2(ADA)2Ni(R,S-Me6cyclam)] (6) results in bridging monoperiodic uranyl-containing subunits into neutral, diperiodic networks. [UO2(ADA)(DMPU)] (7), containing coordinated N,N’-dimethylpropyleneurea, is also a diperiodic assembly with the common fes topol. type. Except complex 6 which is non-luminescent, all complexes give solid-state emission spectra displaying the usual vibronic fine structure, albeit with low photoluminescence quantum yields. In the experiment, the researchers used many compounds, for example, Methyltriphenylphosphonium bromide(cas: 1779-49-3Electric Literature of C19H18BrP)

Methyltriphenylphosphonium bromide(cas: 1779-49-3) is a lipophilic molecule with a cation allowing for it to be used to deliver molecules to specific cell components. Also considered an antineoplastic agent.Electric Literature of C19H18BrP

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary