Category: 162258-89-1

Murphy, Sean et al. published their research in Journal of Organic Chemistry in 1995 | CAS: 162258-89-1

4-Bromo-4′-tert-butylbiphenyl (cas: 162258-89-1) belongs to organobromine compounds. Most of the natural organobromine compounds are produced by marine organisms, and several brominated metabolites with antibacterial, antitumor, antiviral, and antifungal activity have been isolated from seaweed, sponges, corals, molluscs, and others. Commercially available organobromine pharmaceuticals include the vasodilator nicergoline, the sedative brotizolam, the anticancer agent pipobroman, and the antiseptic merbromin. Reference of 162258-89-1

Cyanine Borate Salts that Form Penetrated Ion Pairs in Benzene Solution: Synthesis, Properties, and Structure was written by Murphy, Sean;Yang, Xiquiang;Schuster, Gary B.. And the article was included in Journal of Organic Chemistry in 1995.Reference of 162258-89-1 This article mentions the following:

A series of cyanine borate salts were prepared and studied by laser spectroscopy, fluorescence spectroscopy, NMR spectral methods, and computer modeling. Anal. of the chem., phys., and spectral properties of these salts shows that, in benzene solution, they form penetrated ion pairs. The center-to-center distance between the ions is less than the sum of the individual ionic radii. We call such structures penetrated ion pairs. Penetration affects the properties of the cyanine dyes in unique ways that are described. In the experiment, the researchers used many compounds, for example, 4-Bromo-4′-tert-butylbiphenyl (cas: 162258-89-1Reference of 162258-89-1).

4-Bromo-4′-tert-butylbiphenyl (cas: 162258-89-1) belongs to organobromine compounds. Most of the natural organobromine compounds are produced by marine organisms, and several brominated metabolites with antibacterial, antitumor, antiviral, and antifungal activity have been isolated from seaweed, sponges, corals, molluscs, and others. Commercially available organobromine pharmaceuticals include the vasodilator nicergoline, the sedative brotizolam, the anticancer agent pipobroman, and the antiseptic merbromin. Reference of 162258-89-1

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Ohno, Toshinobu et al. published their research in Journal of Organic Chemistry in 2001 | CAS: 162258-89-1

4-Bromo-4′-tert-butylbiphenyl (cas: 162258-89-1) belongs to organobromine compounds. Bromine is more electronegative than carbon (2.9 vs 2.5). Consequently, the carbon in a carbon闂佺偨鍎茶ぐ绲﹐mine bond is electrophilic, i.e. alkyl bromides are alkylating agents. Many of the alkyl bromine derivatives are excellent alkylating agents since bromides are good leaving groups. Tribromides, like tetrabutylammonium tribromide, are used as a solid source of bromine. N-bromosuccimide (NBS) is used for the selective bromination of allylic bonds.Synthetic Route of C16H17Br

Intramolecular Charge-Transfer Interaction in a New Dyad Based on C60 and Bis(4′-tert-butylbiphenyl-4-yl)aniline (BBA) Donor was written by Ohno, Toshinobu;Moriwaki, Kazuyuki;Miyata, Toshiyuki. And the article was included in Journal of Organic Chemistry in 2001.Synthetic Route of C16H17Br This article mentions the following:

A novel methanofullerene dyad based on C60 and bis(4′-tert-butylbiphenyl-4-yl)aniline (BBA) has been prepared and characterized. Cyclic voltammetry (CV) and UV-vis spectra of the C60-BBA methanofullerene dyad, 61-phenyl-1,2-methanofullerene[60], 1,2-methanofullerene[60], and BBA were measured and analyzed. CV measurements showed that a reversible oxidation wave of the C60-BBA methanofullerene dyad was pos. shifted by 40 mV compared to that of BBA. More remarkably, comparing UV-vis spectra of the C60-BBA methanofullerene dyad and 1,2-methanofullerene[60] shows a large increase in intensity for a broad band at 500 nm in the dyad despite the lack of an absorbance at >400 nm for BBA. These results indicate the presence of charge-transfer interactions in the C60-BBA methanofullerene dyad between the fullerene moiety and diarylaniline moieties. In the experiment, the researchers used many compounds, for example, 4-Bromo-4′-tert-butylbiphenyl (cas: 162258-89-1Synthetic Route of C16H17Br).

4-Bromo-4′-tert-butylbiphenyl (cas: 162258-89-1) belongs to organobromine compounds. Bromine is more electronegative than carbon (2.9 vs 2.5). Consequently, the carbon in a carbon闂佺偨鍎茶ぐ绲﹐mine bond is electrophilic, i.e. alkyl bromides are alkylating agents. Many of the alkyl bromine derivatives are excellent alkylating agents since bromides are good leaving groups. Tribromides, like tetrabutylammonium tribromide, are used as a solid source of bromine. N-bromosuccimide (NBS) is used for the selective bromination of allylic bonds.Synthetic Route of C16H17Br

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Thunga, Sanjeeva et al. published their research in Tetrahedron Letters in 2019 | CAS: 162258-89-1

4-Bromo-4′-tert-butylbiphenyl (cas: 162258-89-1) belongs to organobromine compounds. Many of the organo bromine compounds are relatively nonpolar. Bromine is more electronegative than carbon (2.8 vs 2.5) and hence the carbon in a carbon鑱砨romine bond is electrophilic in nature. Commercially available organobromine pharmaceuticals include the vasodilator nicergoline, the sedative brotizolam, the anticancer agent pipobroman, and the antiseptic merbromin. Computed Properties of C16H17Br

An efficient Pd(II)-(2-aminonicotinaldehyde) complex as complementary catalyst for the Suzuki-Miyaura coupling in water was written by Thunga, Sanjeeva;Poshala, Soumya;Anugu, Naveenkumar;Konakanchi, Ramaiah;Vanaparthi, Satheesh;Kokatla, Hari Prasad. And the article was included in Tetrahedron Letters in 2019.Computed Properties of C16H17Br This article mentions the following:

An efficient new Pd(II)-(2-aminonicotinaldehyde)-catalyzed Suzuki-Miyaura coupling of the aryl halides RX (R = Ph, thiophen-2-yl, 4-(imidazo[1,2-a]pyridin-2-yl)phenyl, etc.; X = Br, Cl, I) and organoboronic acids ArB(OH)2 (Ar = Ph, 3,5-dimethylphenyl, naphthalen-1-yl, etc.) at moderate temperature in water is described. Low catalyst loading, easy accessibility, being an air-stable catalyst, functional group compatibility, and water as the reaction medium are some of the key features of this synthetic method. This protocol is also applicable for gram scale. In the experiment, the researchers used many compounds, for example, 4-Bromo-4′-tert-butylbiphenyl (cas: 162258-89-1Computed Properties of C16H17Br).

4-Bromo-4′-tert-butylbiphenyl (cas: 162258-89-1) belongs to organobromine compounds. Many of the organo bromine compounds are relatively nonpolar. Bromine is more electronegative than carbon (2.8 vs 2.5) and hence the carbon in a carbon鑱砨romine bond is electrophilic in nature. Commercially available organobromine pharmaceuticals include the vasodilator nicergoline, the sedative brotizolam, the anticancer agent pipobroman, and the antiseptic merbromin. Computed Properties of C16H17Br

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Kennedy, Robert D. et al. published their research in Chemistry – A European Journal in 2012 | CAS: 162258-89-1

4-Bromo-4′-tert-butylbiphenyl (cas: 162258-89-1) belongs to organobromine compounds. Bromine is more electronegative than carbon (2.9 vs 2.5). Consequently, the carbon in a carbon閳ユ彽romine bond is electrophilic, i.e. alkyl bromides are alkylating agents. Commercially available organobromine pharmaceuticals include the vasodilator nicergoline, the sedative brotizolam, the anticancer agent pipobroman, and the antiseptic merbromin. Name: 4-Bromo-4′-tert-butylbiphenyl

Crystal-Packing Trends for a Series of 6,9,12,15,18-Pentaaryl-1-hydro[60]fullerenes was written by Kennedy, Robert D.;Halim, Merissa;Khan, Saeed I.;Schwartz, Benjamin J.;Tolbert, Sarah H.;Rubin, Yves. And the article was included in Chemistry – A European Journal in 2012.Name: 4-Bromo-4′-tert-butylbiphenyl This article mentions the following:

The relationship between the size of the substituents of aryl groups in a series of fifteen 6,9,12,15,18-pentaaryl-1-hydro[60]fullerenes and the solid-state structures and packing motifs of these compounds has been analyzed. Pentaarylfullerenes have a characteristic “badminton shuttlecock” shape that causes several derivatives to crystallize into columnar stacks. However, many pentaarylfullerenes form non-stacked structures with, for example, dimeric, layered, diamondoid, or feather-in-cavity relationships between mols. Computational modeling gave a qual. estimate of the best shape match between the ball and socket surfaces of each pentaarylfullerene. The best match was for pentaarylfullerenes with large, spherically shaped para-substituents on the aryl groups. The series of pentaarylfullerenes was characterized by single-crystal X-ray diffraction. A total of 34 crystal structures were obtained as various solvates and were categorized by their packing motifs. In the experiment, the researchers used many compounds, for example, 4-Bromo-4′-tert-butylbiphenyl (cas: 162258-89-1Name: 4-Bromo-4′-tert-butylbiphenyl).

4-Bromo-4′-tert-butylbiphenyl (cas: 162258-89-1) belongs to organobromine compounds. Bromine is more electronegative than carbon (2.9 vs 2.5). Consequently, the carbon in a carbon閳ユ彽romine bond is electrophilic, i.e. alkyl bromides are alkylating agents. Commercially available organobromine pharmaceuticals include the vasodilator nicergoline, the sedative brotizolam, the anticancer agent pipobroman, and the antiseptic merbromin. Name: 4-Bromo-4′-tert-butylbiphenyl

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Yu, Kang-ping et al. published their research in Xiandai Nongyao in 2015 | CAS: 162258-89-1

4-Bromo-4′-tert-butylbiphenyl (cas: 162258-89-1) belongs to organobromine compounds. A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. Organobromine compounds have fallen under increased scrutiny for their environmental impact. In the pharmaceutical industry organo bromine derivatives are used as sedatives, vasodilators, antiseptic agents, and anticancer agents.Safety of 4-Bromo-4′-tert-butylbiphenyl

Synthesis and fungicidal activities of boscalid and its analogs was written by Yu, Kang-ping;Li, Ze-fang;Yin, Hong-bo;Liu, Mu-lan;Li, Hui. And the article was included in Xiandai Nongyao in 2015.Safety of 4-Bromo-4′-tert-butylbiphenyl This article mentions the following:

A novel method was employed for preparing boscalid and its alkyl analogs via Friedel-Crafts alkylation, nitration, reduction, condensation, and reverse Friedel-Crafts alkylation from 4-halobiphenyl. Then boscalid and seven analogs were confirmed by 1H NMR, mass spectrum and IR anal. Preliminary bioassays indicated that the target compounds were effective to some of tested pathogens at 50 mg/L. In the experiment, the researchers used many compounds, for example, 4-Bromo-4′-tert-butylbiphenyl (cas: 162258-89-1Safety of 4-Bromo-4′-tert-butylbiphenyl).

4-Bromo-4′-tert-butylbiphenyl (cas: 162258-89-1) belongs to organobromine compounds. A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. Organobromine compounds have fallen under increased scrutiny for their environmental impact. In the pharmaceutical industry organo bromine derivatives are used as sedatives, vasodilators, antiseptic agents, and anticancer agents.Safety of 4-Bromo-4′-tert-butylbiphenyl

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Murphy, Sean et al. published their research in Journal of Organic Chemistry in 1995 | CAS: 162258-89-1

4-Bromo-4′-tert-butylbiphenyl (cas: 162258-89-1) belongs to organobromine compounds. Most of the natural organobromine compounds are produced by marine organisms, and several brominated metabolites with antibacterial, antitumor, antiviral, and antifungal activity have been isolated from seaweed, sponges, corals, molluscs, and others. Commercially available organobromine pharmaceuticals include the vasodilator nicergoline, the sedative brotizolam, the anticancer agent pipobroman, and the antiseptic merbromin. Reference of 162258-89-1

Cyanine Borate Salts that Form Penetrated Ion Pairs in Benzene Solution: Synthesis, Properties, and Structure was written by Murphy, Sean;Yang, Xiquiang;Schuster, Gary B.. And the article was included in Journal of Organic Chemistry in 1995.Reference of 162258-89-1 This article mentions the following:

A series of cyanine borate salts were prepared and studied by laser spectroscopy, fluorescence spectroscopy, NMR spectral methods, and computer modeling. Anal. of the chem., phys., and spectral properties of these salts shows that, in benzene solution, they form penetrated ion pairs. The center-to-center distance between the ions is less than the sum of the individual ionic radii. We call such structures penetrated ion pairs. Penetration affects the properties of the cyanine dyes in unique ways that are described. In the experiment, the researchers used many compounds, for example, 4-Bromo-4′-tert-butylbiphenyl (cas: 162258-89-1Reference of 162258-89-1).

4-Bromo-4′-tert-butylbiphenyl (cas: 162258-89-1) belongs to organobromine compounds. Most of the natural organobromine compounds are produced by marine organisms, and several brominated metabolites with antibacterial, antitumor, antiviral, and antifungal activity have been isolated from seaweed, sponges, corals, molluscs, and others. Commercially available organobromine pharmaceuticals include the vasodilator nicergoline, the sedative brotizolam, the anticancer agent pipobroman, and the antiseptic merbromin. Reference of 162258-89-1

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Ohno, Toshinobu et al. published their research in Journal of Organic Chemistry in 2001 | CAS: 162258-89-1

4-Bromo-4′-tert-butylbiphenyl (cas: 162258-89-1) belongs to organobromine compounds. Bromine is more electronegative than carbon (2.9 vs 2.5). Consequently, the carbon in a carbon閳ユ彽romine bond is electrophilic, i.e. alkyl bromides are alkylating agents. Many of the alkyl bromine derivatives are excellent alkylating agents since bromides are good leaving groups. Tribromides, like tetrabutylammonium tribromide, are used as a solid source of bromine. N-bromosuccimide (NBS) is used for the selective bromination of allylic bonds.Synthetic Route of C16H17Br

Intramolecular Charge-Transfer Interaction in a New Dyad Based on C60 and Bis(4′-tert-butylbiphenyl-4-yl)aniline (BBA) Donor was written by Ohno, Toshinobu;Moriwaki, Kazuyuki;Miyata, Toshiyuki. And the article was included in Journal of Organic Chemistry in 2001.Synthetic Route of C16H17Br This article mentions the following:

A novel methanofullerene dyad based on C60 and bis(4′-tert-butylbiphenyl-4-yl)aniline (BBA) has been prepared and characterized. Cyclic voltammetry (CV) and UV-vis spectra of the C60-BBA methanofullerene dyad, 61-phenyl-1,2-methanofullerene[60], 1,2-methanofullerene[60], and BBA were measured and analyzed. CV measurements showed that a reversible oxidation wave of the C60-BBA methanofullerene dyad was pos. shifted by 40 mV compared to that of BBA. More remarkably, comparing UV-vis spectra of the C60-BBA methanofullerene dyad and 1,2-methanofullerene[60] shows a large increase in intensity for a broad band at 500 nm in the dyad despite the lack of an absorbance at >400 nm for BBA. These results indicate the presence of charge-transfer interactions in the C60-BBA methanofullerene dyad between the fullerene moiety and diarylaniline moieties. In the experiment, the researchers used many compounds, for example, 4-Bromo-4′-tert-butylbiphenyl (cas: 162258-89-1Synthetic Route of C16H17Br).

4-Bromo-4′-tert-butylbiphenyl (cas: 162258-89-1) belongs to organobromine compounds. Bromine is more electronegative than carbon (2.9 vs 2.5). Consequently, the carbon in a carbon閳ユ彽romine bond is electrophilic, i.e. alkyl bromides are alkylating agents. Many of the alkyl bromine derivatives are excellent alkylating agents since bromides are good leaving groups. Tribromides, like tetrabutylammonium tribromide, are used as a solid source of bromine. N-bromosuccimide (NBS) is used for the selective bromination of allylic bonds.Synthetic Route of C16H17Br

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Thunga, Sanjeeva et al. published their research in Tetrahedron Letters in 2019 | CAS: 162258-89-1

4-Bromo-4′-tert-butylbiphenyl (cas: 162258-89-1) belongs to organobromine compounds. Many of the organo bromine compounds are relatively nonpolar. Bromine is more electronegative than carbon (2.8 vs 2.5) and hence the carbon in a carbon–bromine bond is electrophilic in nature. Commercially available organobromine pharmaceuticals include the vasodilator nicergoline, the sedative brotizolam, the anticancer agent pipobroman, and the antiseptic merbromin. Computed Properties of C16H17Br

An efficient Pd(II)-(2-aminonicotinaldehyde) complex as complementary catalyst for the Suzuki-Miyaura coupling in water was written by Thunga, Sanjeeva;Poshala, Soumya;Anugu, Naveenkumar;Konakanchi, Ramaiah;Vanaparthi, Satheesh;Kokatla, Hari Prasad. And the article was included in Tetrahedron Letters in 2019.Computed Properties of C16H17Br This article mentions the following:

An efficient new Pd(II)-(2-aminonicotinaldehyde)-catalyzed Suzuki-Miyaura coupling of the aryl halides RX (R = Ph, thiophen-2-yl, 4-(imidazo[1,2-a]pyridin-2-yl)phenyl, etc.; X = Br, Cl, I) and organoboronic acids ArB(OH)2 (Ar = Ph, 3,5-dimethylphenyl, naphthalen-1-yl, etc.) at moderate temperature in water is described. Low catalyst loading, easy accessibility, being an air-stable catalyst, functional group compatibility, and water as the reaction medium are some of the key features of this synthetic method. This protocol is also applicable for gram scale. In the experiment, the researchers used many compounds, for example, 4-Bromo-4′-tert-butylbiphenyl (cas: 162258-89-1Computed Properties of C16H17Br).

4-Bromo-4′-tert-butylbiphenyl (cas: 162258-89-1) belongs to organobromine compounds. Many of the organo bromine compounds are relatively nonpolar. Bromine is more electronegative than carbon (2.8 vs 2.5) and hence the carbon in a carbon–bromine bond is electrophilic in nature. Commercially available organobromine pharmaceuticals include the vasodilator nicergoline, the sedative brotizolam, the anticancer agent pipobroman, and the antiseptic merbromin. Computed Properties of C16H17Br

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Kennedy, Robert D. et al. published their research in Chemistry – A European Journal in 2012 | CAS: 162258-89-1

4-Bromo-4′-tert-butylbiphenyl (cas: 162258-89-1) belongs to organobromine compounds. Bromine is more electronegative than carbon (2.9 vs 2.5). Consequently, the carbon in a carbon–bromine bond is electrophilic, i.e. alkyl bromides are alkylating agents. Commercially available organobromine pharmaceuticals include the vasodilator nicergoline, the sedative brotizolam, the anticancer agent pipobroman, and the antiseptic merbromin. Name: 4-Bromo-4′-tert-butylbiphenyl

Crystal-Packing Trends for a Series of 6,9,12,15,18-Pentaaryl-1-hydro[60]fullerenes was written by Kennedy, Robert D.;Halim, Merissa;Khan, Saeed I.;Schwartz, Benjamin J.;Tolbert, Sarah H.;Rubin, Yves. And the article was included in Chemistry – A European Journal in 2012.Name: 4-Bromo-4′-tert-butylbiphenyl This article mentions the following:

The relationship between the size of the substituents of aryl groups in a series of fifteen 6,9,12,15,18-pentaaryl-1-hydro[60]fullerenes and the solid-state structures and packing motifs of these compounds has been analyzed. Pentaarylfullerenes have a characteristic “badminton shuttlecock” shape that causes several derivatives to crystallize into columnar stacks. However, many pentaarylfullerenes form non-stacked structures with, for example, dimeric, layered, diamondoid, or feather-in-cavity relationships between mols. Computational modeling gave a qual. estimate of the best shape match between the ball and socket surfaces of each pentaarylfullerene. The best match was for pentaarylfullerenes with large, spherically shaped para-substituents on the aryl groups. The series of pentaarylfullerenes was characterized by single-crystal X-ray diffraction. A total of 34 crystal structures were obtained as various solvates and were categorized by their packing motifs. In the experiment, the researchers used many compounds, for example, 4-Bromo-4′-tert-butylbiphenyl (cas: 162258-89-1Name: 4-Bromo-4′-tert-butylbiphenyl).

4-Bromo-4′-tert-butylbiphenyl (cas: 162258-89-1) belongs to organobromine compounds. Bromine is more electronegative than carbon (2.9 vs 2.5). Consequently, the carbon in a carbon–bromine bond is electrophilic, i.e. alkyl bromides are alkylating agents. Commercially available organobromine pharmaceuticals include the vasodilator nicergoline, the sedative brotizolam, the anticancer agent pipobroman, and the antiseptic merbromin. Name: 4-Bromo-4′-tert-butylbiphenyl

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Yu, Kang-ping et al. published their research in Xiandai Nongyao in 2015 | CAS: 162258-89-1

4-Bromo-4′-tert-butylbiphenyl (cas: 162258-89-1) belongs to organobromine compounds. A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. Organobromine compounds have fallen under increased scrutiny for their environmental impact. In the pharmaceutical industry organo bromine derivatives are used as sedatives, vasodilators, antiseptic agents, and anticancer agents.Safety of 4-Bromo-4′-tert-butylbiphenyl

Synthesis and fungicidal activities of boscalid and its analogs was written by Yu, Kang-ping;Li, Ze-fang;Yin, Hong-bo;Liu, Mu-lan;Li, Hui. And the article was included in Xiandai Nongyao in 2015.Safety of 4-Bromo-4′-tert-butylbiphenyl This article mentions the following:

A novel method was employed for preparing boscalid and its alkyl analogs via Friedel-Crafts alkylation, nitration, reduction, condensation, and reverse Friedel-Crafts alkylation from 4-halobiphenyl. Then boscalid and seven analogs were confirmed by 1H NMR, mass spectrum and IR anal. Preliminary bioassays indicated that the target compounds were effective to some of tested pathogens at 50 mg/L. In the experiment, the researchers used many compounds, for example, 4-Bromo-4′-tert-butylbiphenyl (cas: 162258-89-1Safety of 4-Bromo-4′-tert-butylbiphenyl).

4-Bromo-4′-tert-butylbiphenyl (cas: 162258-89-1) belongs to organobromine compounds. A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. Organobromine compounds have fallen under increased scrutiny for their environmental impact. In the pharmaceutical industry organo bromine derivatives are used as sedatives, vasodilators, antiseptic agents, and anticancer agents.Safety of 4-Bromo-4′-tert-butylbiphenyl

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary