Synthesis of oxadiazole-2-oxide analogues as potential antischistosomal agents was written by Rai, Ganesha;Thomas, Craig J.;Leister, William;Maloney, David J.. And the article was included in Tetrahedron Letters in 2009.Electric Literature of C9H6BrFO2 This article mentions the following:
The synthesis of a series of 4,5-disubstituted furoxans, 1,2,5-oxadiazole-2-oxides I (e.g., R1 = 4-F, 3-CF3, etc) was described. These compounds were prepared in an effort to probe the SAR around the Ph substituent and oxadiazole core for studies toward thioredoxin-glutathione reductase (TGR) inhibition and antischistosomal activity. In the experiment, the researchers used many compounds, for example, 3-Bromo-4-fluorocinnamic acid (cas: 160434-49-1Electric Literature of C9H6BrFO2).
3-Bromo-4-fluorocinnamic acid (cas: 160434-49-1) belongs to organobromine compounds. Organo bromine compounds are versatile compounds and are widely used in diverse fields. Organo bromine derivatives are used in the dye sector, as an indicator in analytical chemistry (Bromothymol blue is a popular indicator). The reactivity of organobromine compounds resembles but is intermediate between the reactivity of organochlorine and organoiodine compounds. For many applications, organobromides represent a compromise of reactivity and cost.Electric Literature of C9H6BrFO2
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary