Application of 15378-31-1, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 15378-31-1, name is 3-Bromo-2-(bromomethyl)prop-1-ene belongs to bromides-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below.
6.3 g of KF are added at -15 C. under nitrogen and with stirring to a solution of 21.8 g of trifluoromethyl trifluoromethanesulfonate in 50 ml of dry N,N-dimethylacetamide (DMA) in a three-necked flask with dry-ice condenser, and the mixture is stirred at this temperature for 0.5 hour. Gaseous trifluoromethanesulfonyl fluoride and a DMA suspension of potassium trifluoromethanolate form. 21.4 g of the dibromide are metered into the suspension, and the mixture is stirred at 50-60 C. for 24 hours. In order to isolate the product, the reaction mixture is cooled to room temperature and added to ice. The organic phase is separated off at 0 C., and the remaining phase is distilled at atmospheric pressure. A colourless, mobile liquid forms.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 3-Bromo-2-(bromomethyl)prop-1-ene, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; MERCK PATENT GESELLSCHAFT MIT DESCHRANKTER HAFTUNG; US2011/82312; (2011); A1;,
Bromide – Wikipedia,
bromide – Wiktionary