Category: 1530-33-2

Qin, Pengjin; Wang, Li-An; O’Connor, Joseph M.; Baldridge, Kim K.; Li, Yifan; Tufekci, Burak; Chen, Jiyue; Rheingold, Arnold L. published the artcile< Transition-Metal Catalysis of Triene 6π Electrocyclization: The π-Complexation Strategy Realized>, Application of C21H22BrP, the main research area is triene electrocyclization transition metal pi complexation catalysis; catalysis; cycloaromatization; electrocyclization; transition metals; triene.

Triene 6π electrocyclization, wherein a conjugated triene undergoes a concerted stereospecific cycloisomerization to a cyclohexadiene, is a reaction of great historical and practical significance. In order to circumvent limitations imposed by the normally harsh reaction conditions, chemists have long sought to develop catalytic variants based upon the activating power of metal-alkene coordination. Herein, we demonstrate the first successful implementation of such a strategy by utilizing [(C5H5)Ru(NCMe)3]PF6 as a precatalyst for the disrotatory 6π electrocyclization of highly substituted trienes that are resistant to thermal cyclization. Mechanistic and computational studies implicate hexahapto transition-metal coordination as responsible for lowering the energetic barrier to ring closure. This work establishes a foundation for the development of new catalysts for stereoselective electrocyclizations.

Angewandte Chemie, International Edition published new progress about Alkatrienes Role: PEP (Physical, Engineering or Chemical Process), PRP (Properties), RCT (Reactant), SPN (Synthetic Preparation), PROC (Process), RACT (Reactant or Reagent), PREP (Preparation). 1530-33-2 belongs to class bromides-buliding-blocks, and the molecular formula is C21H22BrP, Application of C21H22BrP.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Dong, Kui; Jin, Xiao-Ling; Chen, Shihao; Wu, Li-Zhu; Liu, Qiang published the artcile< Controllable synthesis of 2- and 3-aryl-benzomorpholines from 2-aminophenols and 4-vinylphenols>, Category: bromides-buliding-blocks, the main research area is aryl benzomorpholine preparation diastereoselective chemoselective regioselective; aminophenol vinylphenol cross coupling heterocyclization rose bengal photocatalyst.

Herein, a method for the controllable synthesis of 3-aryl-benzomorpholine and 2-aryl-benzomorpholine cycloadducts I (R1 = H, 5-Me, 6-t-Bu, 6-Br, etc.; R2 = H, Me, Ph, Bn; R3 = H, Me, OMe, t-Bu; R4 = Me, OMe, OEt, t-Bu; R5 = Me, Et, OMe, CH1OH; R6 = H, Me) and II (R7 = H, 5-Me, 6-Br, 7-Cl, etc.; R8 = H, OMe, OEt, t-Bu) via cross-coupling/annulation between electron-rich 2-aminophenols 2-NH(R2)R1C6H3OH/2-NH2-R7C6H3OH and 4-vinylphenols 3-R3-4-OH-5-R4C6H2CH=CH(R5)R6/ 3-R3-4-OH-5-R8C6H2CH=CH(R5)R6 was presented. Mol. oxygen was successfully used in the reaction as the terminal oxidant and the complete inversion of chemoselectivity was achieved by the adjustment of the solvents and bases at room temperature

Chemical Communications (Cambridge, United Kingdom) published new progress about Chemoselectivity. 1530-33-2 belongs to class bromides-buliding-blocks, and the molecular formula is C21H22BrP, Category: bromides-buliding-blocks.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Chen, Mintao; Zang, Wenqing; Wei, Yin; Shi, Min published the artcile< A highly efficient method for the construction of cyclopropane-containing dihydroindole derivatives from indolemethylenecyclopropanes with DIAD and DEAD>, Quality Control of 1530-33-2, the main research area is cyclopropane dihydroindole derivative preparation indolemethylenecyclopropane DIAD DEAD.

A highly efficient method for the construction of cyclopropane-containing dihydroindole derivatives from indolemethylenecyclopropanes with DIAD and DEAD was disclosed. The transformation could occur under catalyst-free conditions at ambient temperature to afford dihyroindole derivatives in good yields. The strained moiety of methylenecyclopropane in the substrate of indolemethylenecyclopropane is critical and DFT calculations reveal that the reaction proceeds through a two-step pathway.

Organic & Biomolecular Chemistry published new progress about Crystal structure. 1530-33-2 belongs to class bromides-buliding-blocks, and the molecular formula is C21H22BrP, Quality Control of 1530-33-2.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary