14516-54-2 Archives - Bromides-buliding-blocks

Ling, Fei’s team published research in Synlett in 2020 | CAS: 14516-54-2

Bromopentacarbonylmanganese(I)(cas: 14516-54-2) has many other uses. It is used in the formation of (eta6-arene)tricarbonylmanganese(I) by reacting with arene (arene= hexamethyl benzene, 1,2,4,5-tetramethyl benzene, mesitylene, p-xylene and toluene) in the presence silver salt.Related Products of 14516-54-2

Related Products of 14516-54-2In 2020 ,《Manganese-Catalyzed Enantioselective Hydrogenation of Simple Ketones Using an Imidazole-Based Chiral PNN Tridentate Ligand》 was published in Synlett. The article was written by Ling, Fei; Chen, Jiachen; Nian, Sanfei; Hou, Huacui; Yi, Xiao; Wu, Feifei; Xu, Min; Zhong, Weihui. The article contains the following contents:

A series of Mn(I) catalysts containing imidazole-based chiral PNN tridentate ligands I (R = diphenylphosphanyl, bis(3,5-dimethylphenyl)phosphanyl, bis(propan-2-yl)phosphanyl; R1 = 1-benzyl-1H-imidazol-2-yl, 1-benzyl-1H-1,3-benzodiazol-2-yl, 1-(propan-2-yl)-1H-1,3-benzodiazol-2-yl, etc.) with controllable ‘side arm’ groups have been established, enabling the inexpensive base-promoted asym. hydrogenation of simple ketones R2C(O)R3 (R2 = naphthalen-2-yl, 9H-fluoren-1-yl, benzofuran-2-yl, etc.; R3 = Me, cyclohexyl, propan-2-yl, etc.) and 1,2,3,4-tetrahydronaphthalen-1-one with outstanding activities (up to 8200 TON) and good enantioselectivities (up to 88.5% ee). This protocol features wide substrate scope and functional group tolerance, thereby providing easy access to a key intermediate of crizotinib. The experimental part of the paper was very detailed, including the reaction process of Bromopentacarbonylmanganese(I)(cas: 14516-54-2Related Products of 14516-54-2)

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Tang, Qi’s team published research in Nanoscale in 2022 | CAS: 14516-54-2

In 2022,Tang, Qi; Liu, Jing; Wang, Cheng-Bin; An, Lu; Zhang, Hai-Lin; Wang, Yi; Ren, Bing; Yang, Shi-Ping; Liu, Jin-Gang published an article in Nanoscale. The title of the article was 《A multifunctional nanoplatform delivering carbon monoxide and a cysteine protease inhibitor to mitochondria under NIR light shows enhanced synergistic anticancer efficacy》.Electric Literature of C5BrMnO5 The author mentioned the following in the article:

Photoactivated chemotherapy has attracted widespread attention due to its ability to circumvent the shortcomings of hypoxia in tumor tissues compared with traditional photodynamic therapy. In this work, novel multifunctional nanoplatform (1), Ru-inhibitor@TPPMnCO@N-GQDs, was designed and prepared, which was capable of mitochondria-targeted co-delivery of the cysteine protease inhibitor and carbon monoxide (CO) stimulated with an 808 nm near IR (NIR) laser. Nanoplatform (1) was prepared by covalent attachment of a mitochondria-targeted CO donor (TPPMnCO) and a Ru(II)-caged cysteine protease inhibitor (Ru-inhibitor) on the surface of fluorescent N-doped graphene quantum dots (N-GQDs). Nanoplatform (1) preferentially accumulated in the mitochondria of cancer cells and instantly delivered CO and the cysteine protease inhibitor upon 808 nm NIR light irradiation, thus damaging mitochondria and leading to significant in vitro and in vivo anticancer efficacy. In addition, nanoplatform (1) has good biocompatibility and did not exert any toxic side effects on mice during the period of treatment. The targeted subcellular mitochondrial co-delivery of CO and the cysteine protease inhibitor may provide new insights into CO and enzyme inhibitor combined therapies for cancer treatment. The experimental part of the paper was very detailed, including the reaction process of Bromopentacarbonylmanganese(I)(cas: 14516-54-2Electric Literature of C5BrMnO5)

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Papa, Veronica’s team published research in IUCrData in 2020 | CAS: 14516-54-2

《Bis(benzo[h]quinolin-10-olato-κ2N,O)bromidomanganese(III)》 was published in IUCrData in 2020. These research results belong to Papa, Veronica; Spannenberg, Anke; Beller, Matthias; Junge, Kathrin. Related Products of 14516-54-2 The article mentions the following:

The title compound, [MnBr(C13H8NO)2], consists of a manganese(III) atom, which is coordinated by one bromido and two benzo[h]quinolin-10-olato ligands. The MnIII complex exhibits a distorted square-pyramidal coordination geometry with the Br ligand in the apical position. Neighboring complexes are held together by π-π interactions and weak C-H···Br hydrogen bonds. In the experiment, the researchers used many compounds, for example, Bromopentacarbonylmanganese(I)(cas: 14516-54-2Related Products of 14516-54-2)

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Friaes, Sofia’s team published research in Molecules in 2021 | CAS: 14516-54-2

Friaes, Sofia; Realista, Sara; Gomes, Clara S. B.; Martinho, Paulo N.; Royo, Beatriz published an article in 2021. The article was titled 《Click-Derived Triazoles and Triazolylidenes of Manganese for Electrocatalytic Reduction of CO2†》, and you may find the article in Molecules.Related Products of 14516-54-2 The information in the text is summarized as follows:

A series of new fac-[Mn(L)(CO)3Br] complexes where L is a bidentate chelating ligand containing mixed mesoionic triazolylidene-pyridine (MIC^py, 1), triazolylidene-triazole (MIC^trz, 2), and triazole-pyridine (trz^py, 3) ligands have been prepared and fully characterized, including the single crystal X-ray diffraction studies of 1 and 2. The abilities of 1-3 and complex fac-[Mn(MIC^MIC)(CO)3Br] (4) to catalyze the electroreduction of CO2 has been assessed for the first time. It was found that all complexes displayed a current increase under CO2 atm, being 3 and 4 the most active complexes. Complex 3, bearing a N^N-based ligand exhibited a good efficiency and an excellent selectivity for reducing CO2 to CO in the presence of 1.0 M of water, at low overpotential. Interestingly, complex 4 containing the strongly electron donating di-imidazolylidene ligand exhibited comparable activity to 3, when the experiments were performed in neat acetonitrile at slightly higher overpotential (-1.86 vs. -2.14 V). In the experiment, the researchers used many compounds, for example, Bromopentacarbonylmanganese(I)(cas: 14516-54-2Related Products of 14516-54-2)

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Gausas, Laurynas’s team published research in JACS Au in 2021 | CAS: 14516-54-2

Computed Properties of C5BrMnO5In 2021 ,《Catalytic Hydrogenation of Polyurethanes to Base Chemicals: From Model Systems to Commercial and End-of-Life Polyurethane Materials》 appeared in JACS Au. The author of the article were Gausas, Laurynas; Kristensen, Steffan K.; Sun, Hongwei; Ahrens, Alexander; Donslund, Bjarke S.; Lindhardt, Anders T.; Skrydstrup, Troels. The article conveys some information:

Polyurethane (PU) is a highly valued polymer prepared from diisocyanates and polyols, and it is used in everyday products, such as shoe soles, mattresses, and insulation materials, but also for the construction of sophisticated parts of medical devices, wind turbine blades, aircrafts, and spacecrafts, to name a few. As PU is most commonly used as a thermoset polymer composed of cross-linked structures, its recycling is complicated and inefficient, leading to increasing PU waste accumulating every year. Catalytic hydrogenation represents an atom-efficient means for the deconstruction of polyurethanes, but so far the identification of an efficient catalyst for the disassembly of real-life and end-of-life PU samples has not been demonstrated. In this work, we reveal that a com. available catalyst, Ir-iPrMACHO, under 30 bar H2 and 150-180°C, is a general catalyst for the effective hydrogenation of the four cornerstones of PU: flexible solid, flexible foamed, rigid solid, and rigid foamed, leading to the isolation of aromatic amines and a polyol fraction. For the first time, a variety of com. PU materials, including examples of foams, inline skating wheels, shoe soles, and insulation materials, has been deconstructed into the two fractions. Most desirable, our reaction conditions include the use of iso-Pr alc. as a representative of a green solvent. It is speculated that a partial glycolysis at the surface of the PU particles is taking place in this solvent and reaction temperatures in the presence of catalytic amounts of base. As such a more efficient hydrogenation of the solubilized PU fragments in iso-Pr alc. becomes possible. As the isolated anilines are precursors to the original isocyanate building blocks, and methods for their conversion are well-known, the work reported in this paper provides a realistic indication of a potential circular plastic economy solution for PU. Preliminary experiments were also undertaken applying Mn-iPrMACHO for the deconstruction of a com. flexible PU foam. Although successful, more forcing conditions were required than those when applying Ir-iPrMACHO.Bromopentacarbonylmanganese(I)(cas: 14516-54-2Computed Properties of C5BrMnO5) was used in this study.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Das, Kuhali’s team published research in ACS Catalysis in 2021 | CAS: 14516-54-2

Das, Kuhali; Sarkar, Koushik; Maji, Biplab published their research in ACS Catalysis in 2021. The article was titled 《Manganese-Catalyzed Anti-Markovnikov Hydroamination of Allyl Alcohols via Hydrogen-Borrowing Catalysis》.HPLC of Formula: 14516-54-2 The article contains the following contents:

In this article, a selective formal anti-Markovnikov hydroamination of allyl alcs. RCH=C(R1)C(R2)OH (R = H, Me, n-Pr, pent-4-en-1-yl; R1 = H, Me; R2 = H, Me, Ph, furan-2-yl, etc.) is presented. It enables the versatile synthesis of valuable γ-amino alc. building blocks e.g., 3-(methyl(phenyl)amino)propan-1-ol. A phosphine-free Earth’s abundant manganese(I) complex catalyzed the reaction under hydrogen-borrowing conditions. A vast range of amines such as pyrrolidine, aniline, 1H-indoline, morpholine, etc. drug mols., and natural product derivs e.g., I. underwent successful hydroamination with primary and secondary allylic alcs. with excellent functional group tolerance. The catalysis could be performed on a gram scale and has been applied for the synthesis of drug mols. The mechanistic studies revealed the metal-ligand bifunctionality as well as hemilability of the ligand backbone as the key design principle for the success of this catalysis. In the experiment, the researchers used many compounds, for example, Bromopentacarbonylmanganese(I)(cas: 14516-54-2HPLC of Formula: 14516-54-2)

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Yang, Jichun’s team published research in Biomaterials in 2021 | CAS: 14516-54-2

Yang, Jichun; Pan, Shuojiong; Gao, Shiqian; Li, Tianyu; Xu, Huaping published their research in Biomaterials in 2021. The article was titled 《CO/chemosensitization/antiangiogenesis synergistic therapy with H2O2-responsive diselenide-containing polymer》.Recommanded Product: Bromopentacarbonylmanganese(I) The article contains the following contents:

Carbon monoxide (CO) therapy and antiangiogenesis therapy (AAT) are regarded as promising approaches for cancer treatment. However, the poor tumor targeting ability and inevitable side effects prevent their clin. application. In this study, we developed H2O2-responsive diselenide-containing micelles that combined CO therapy with chemosensitization therapy and AAT in a single system. Under the interaction of intratumoral H2O2, CO and gemcitabine (GEM) were released in situ from the micelles to reduce side effects, and CO significantly sensitized the chemotherapeutic effect of GEM by elevating the level of reactive oxygen species (ROS) in human gastric cancer AGS cells. Furthermore, diselenide bonds in the micelles were oxidized to seleninic acid in organic form, which suppressed the expressions of vascular endothelial growth factor (VEGF) and matrix metalloproteinase-2 (MMP-2) to realize AAT. This study provides an integrated solution to combine CO therapy with chemosensitization therapy and AAT together with good biocompatibility. In the experimental materials used by the author, we found Bromopentacarbonylmanganese(I)(cas: 14516-54-2Recommanded Product: Bromopentacarbonylmanganese(I))

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Gonzalez, Tania’s team published research in Polyhedron in 2021 | CAS: 14516-54-2

Gonzalez, Tania; Garcia, Juventino J. published an article in 2021. The article was titled 《Catalytic CO2 hydrosilylation with [Mn(CO)5Br] under mild reaction conditions》, and you may find the article in Polyhedron.Formula: C5BrMnO5 The information in the text is summarized as follows:

Carbon dioxide hydrosilylation with earth-abundant transition-metal catalysts is an attractive alternative for the design of greener and cost-effective synthetic strategies. Herein, simple [Mn(CO)5Br] is an efficient precatalyst in the hydrosilylation of carbon dioxide with Et3SiH under mild reaction conditions. Using THF as a solvent, triethylsilylformate Et3SiCH(O)O was obtained in 67% yield after 1 h at 50°C and 4 bar of CO2 pressure. The selectivity of the reaction was tuned by changing the solvent to a mixture of THF and toluene producing bis(triethylsilyl)acetal (Et3SiO)2CH2 in 86% yield. The CO2 hydrosilylation was also effective at room temperature and atm. pressure using either THF or the mixture THF/toluene as the solvent resulting in high Et3SiH conversion (92%-99%) but with a decrease in the selectivity. Radical trapping experiments indicated the participation of radical species in the catalytic mechanism. To the best of our knowledge, this is the first report on CO2 hydrosilylation catalyzed by transition-metal radical intermediates. In addition to this study using Bromopentacarbonylmanganese(I), there are many other studies that have used Bromopentacarbonylmanganese(I)(cas: 14516-54-2Formula: C5BrMnO5) was used in this study.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Yadav, Vinita’s team published research in ACS Catalysis in 2020 | CAS: 14516-54-2

《Manganese Catalyzed α-Olefination of Nitriles with Secondary Alcohols》 was published in ACS Catalysis in 2020. These research results belong to Yadav, Vinita; Landge, Vinod G.; Subaramanian, Murugan; Balaraman, Ekambaram. COA of Formula: C5BrMnO5 The article mentions the following:

An expedient catalytic approach for α-olefination of nitriles using secondary alcs. with the liberation of mol. hydrogen and water as the only byproducts is reported. This reaction is catalyzed by a molecularly defined manganese(I) pincer complex and operates in the absence of any hydrogen acceptors. A broad range of substrates including cyclic, acy-clic, and benzylic alcs. as well as various nitrile derivatives such as arylmethyl and hetroarylmethyl nitriles are employed in the reaction to provide diverse range of α-vinyl nitriles in good to excellent yields. Mechanistic studies showed that the reaction proceeds via dehydrogenative pathway and the activation of α(C-H) bond of the alc. is the rate determining step. Kinetic experiments clearly indicate the first order rate kinetics for alcs. as well as nitriles.Bromopentacarbonylmanganese(I)(cas: 14516-54-2COA of Formula: C5BrMnO5) was used in this study.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Yang, Yong’s team published research in Chemical Science in 2021 | CAS: 14516-54-2

Yang, Yong; Ertem, Mehmed Z.; Duan, Lele published an article in 2021. The article was titled 《An amide-based second coordination sphere promotes the dimer pathway of Mn-catalyzed CO2-to-CO reduction at low overpotential》, and you may find the article in Chemical Science.Related Products of 14516-54-2 The information in the text is summarized as follows:

The [fac-Mn(bpy)(CO)3Br] complex is capable of catalyzing the electrochem. reduction of CO2 to CO with high selectivity, moderate activity and large overpotential. Several attempts have been made to lower the overpotential and to enhance the catalytic activity of this complex by manipulating the second-coordination sphere of manganese and using relatively stronger acids to promote the protonation-first pathway. We report herein that the complex [fac-Mn(bpy-CONHMe)(CO)3(MeCN)]+ ([1-MeCN]+; bpy-CONHMe = N-methyl-(2,2′-bipyridine)-6-carboxamide) as a pre-catalyst could catalyze the electrochem. reduction of CO2 to CO with low overpotential and high activity and selectivity. Combined exptl. and computational studies reveal that the amide NH group not only decreases the overpotential of the Mn catalyst by promoting the dimer and protonation-first pathways in the presence of H2O but also enhances the CO2 electroreduction activity by facilitating C-OH bond cleavage, making [1-MeCN]+ an efficient CO2 reduction pre-catalyst at low overpotential. The results came from multiple reactions, including the reaction of Bromopentacarbonylmanganese(I)(cas: 14516-54-2Related Products of 14516-54-2)

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary