Leenders, Ruben’s team published research in Bioorganic & Medicinal Chemistry Letters in 29 | CAS: 1256955-36-8

Bioorganic & Medicinal Chemistry Letters published new progress about 1256955-36-8. 1256955-36-8 belongs to bromides-buliding-blocks, auxiliary class Bromide,Amine,Benzene,Ester,Ether, name is Methyl 2-amino-4-bromo-5-methoxybenzoate, and the molecular formula is C9H10BrNO3, Application In Synthesis of 1256955-36-8.

Leenders, Ruben published the artcileNovel SAR for quinazoline inhibitors of EHMT1 and EHMT2, Application In Synthesis of 1256955-36-8, the publication is Bioorganic & Medicinal Chemistry Letters (2019), 29(17), 2516-2524, database is CAplus and MEDLINE.

Detailed structure activity relationship of two series of quinazoline EHMT1/EHMT2 inhibitor compounds I [R = COOH, CONH2, (5-prop-2-ynylpyrrolidin-2-one)-3-yl etc.] and II [R1 = OMe, F, OCF3 ; R2 = aminopropynyl,(5-prop-2-ynylpyrrolidin-2-one)-3-yl etc.] were elaborated. New and active alternatives were presented for the ubiquitous substitution patterns found in literature for the linker to the lysine mimicking region and the lysine mimic itself.

Bioorganic & Medicinal Chemistry Letters published new progress about 1256955-36-8. 1256955-36-8 belongs to bromides-buliding-blocks, auxiliary class Bromide,Amine,Benzene,Ester,Ether, name is Methyl 2-amino-4-bromo-5-methoxybenzoate, and the molecular formula is C9H10BrNO3, Application In Synthesis of 1256955-36-8.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary