Huang, Pengmian’s team published research in Tetrahedron Letters in 96 | CAS: 1207314-86-0

Tetrahedron Letters published new progress about 1207314-86-0. 1207314-86-0 belongs to bromides-buliding-blocks, auxiliary class Trifluoromethyl,Fluoride,Bromide,Amine,Benzene, name is 2-Bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)aniline, and the molecular formula is C10H4BrF10N, Application of 2-Bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)aniline.

Huang, Pengmian published the artcileDesign, synthesis and insecticidal activities of new meta-diamide compounds containing n-butyl group, Application of 2-Bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)aniline, the publication is Tetrahedron Letters (2022), 153743, database is CAplus.

In order to discover a novel insecticide, a series of meta-diamide compounds containing Bu group were designed and synthesized. Preliminary bioassay data showed that some of the target compounds exhibited good insecticidal activities against Plutella xylostella, Spodoptera frugiperda and Alfalfa sprouts. In particular, compounds 6d and 6n displayed 100% insecticidal activity against Plutella xylostella at 1 mg/L and also revealed 100% of mortality rate against Spodoptera frugiperda at 0.1 mg/L, which was consistent with the cyproflanilide. Meanwhile, compound 6m showed 98.89% insecticidal activity against Alfalfa sprouts at 100 mg/L, better than cyproflanilide (25.60% at 100 mg/L). The work demonstrated that compounds containing Bu group might supply certain hints toward structure optimization design for the development of new insecticides.

Tetrahedron Letters published new progress about 1207314-86-0. 1207314-86-0 belongs to bromides-buliding-blocks, auxiliary class Trifluoromethyl,Fluoride,Bromide,Amine,Benzene, name is 2-Bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)aniline, and the molecular formula is C10H4BrF10N, Application of 2-Bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)aniline.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Luo, Chunyan’s team published research in Youji Huaxue in 40 | CAS: 1207314-86-0

Youji Huaxue published new progress about 1207314-86-0. 1207314-86-0 belongs to bromides-buliding-blocks, auxiliary class Trifluoromethyl,Fluoride,Bromide,Amine,Benzene, name is 2-Bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)aniline, and the molecular formula is C10H4BrF10N, Synthetic Route of 1207314-86-0.

Luo, Chunyan published the artcileSynthesis and insecticidal activity of novel meta-diamide compounds containing cyclopropyl group, Synthetic Route of 1207314-86-0, the publication is Youji Huaxue (2020), 40(9), 2963-2970, database is CAplus.

To discover novel insecticide with improved activity, a series of meta-diamide compounds containing cyclopropyl moiety were synthesized on the principle of biol. active factor splicing. The structures of synthetic derivatives were characterized by 1H NMR, 13C NMR and HRMS. Preliminary bioassay data showed that some of the title compounds exhibited good insecticidal activities against Plutella xylostella and Chilo suppressalis. Among them, the mortality of N-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl) phenyl)-3-(N-(cyclopropylmethyl) benzamido)-2-fluorobenzamide (6d) and 3-(N-(cyclopropylmethyl) benzamido)-N-(2,6-dibromo-4-(perfluoropropan-2-yl) phenyl)-2-fluorobenzamide (6e) was 100% against Plutella xylostella at 1 mg/L, and the mortality of compound 6d was 100% against Chilo suppressalis at 5 mg/L.

Youji Huaxue published new progress about 1207314-86-0. 1207314-86-0 belongs to bromides-buliding-blocks, auxiliary class Trifluoromethyl,Fluoride,Bromide,Amine,Benzene, name is 2-Bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)aniline, and the molecular formula is C10H4BrF10N, Synthetic Route of 1207314-86-0.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary