Category: 111865-47-5

Czollner, Laszlo published the artcileSynthesis of galanthamine, Product Details of C10H16Br3N, the publication is ARKIVOC (Gainesville, FL, United States) [online computer file] (2001), 191-200, database is CAplus.

The synthesis of (±)- and (-)-galanthamine (I) via 3,4-dihydro-6,7-dimethoxy-4′-oxo[spiro-[5H]-2-benzazepine-5,1′-[2]cyclohexene]-2(1H)-carboxylic acid Et ester (II) is described.

ARKIVOC (Gainesville, FL, United States) [online computer file] published new progress about 111865-47-5. 111865-47-5 belongs to bromides-buliding-blocks, auxiliary class Benzenes, name is Mono(N,N,N-trimethyl-1-phenylmethanaminium) tribromide, and the molecular formula is C10H16Br3N, Product Details of C10H16Br3N.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Uchikawa, Yuki published the artcileSynthesis and demethylation of 4,22-dimethoxy[2.10]metacyclophan-1-yne with BBr₃ to afford a novel [10](2,9)-5a,11a-benzofuro-5a-bora-11-bromochromenophane, Category: bromides-buliding-blocks, the publication is Canadian Journal of Chemistry (2012), 90(5), 441-449, database is CAplus.

4,22-Dimethoxy[2.10]metacyclophan-1-yne was prepared by bromination of [2.10]metacyclophan-1-ene followed by the dehydrobromination of the bromine adduct with KOBu-t. Treatment of 4,22-Dimethoxy[2.10]metacyclophan-1-yne with BBr₃ in CH₂Cl₂ at room temperature led to the demethylation and a successive intramol. cyclization reaction to afford a novel [10](2,9)-5a,11a-benzofuro-5a-11-bromochromenophane in good yield. Similar treatment of a mixture of the corresponding meso- and dl-1,2-dibromo-4,22-dimethoxy[2.10]metacyclophane with BBr₃ in CH₂Cl₂ under the same conditions described above afforded cis-4b,9b-dihydro[10]benzofuro[3,2-b]benzofuranophane in 83% yield.

Canadian Journal of Chemistry published new progress about 111865-47-5. 111865-47-5 belongs to bromides-buliding-blocks, auxiliary class Benzenes, name is Mono(N,N,N-trimethyl-1-phenylmethanaminium) tribromide, and the molecular formula is C13H9ClN2O4, Category: bromides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Oka, Hiroyuki published the artcileSynthesis and characterization of poly(1,3-phenylene)-based polyradicals carrying cyclic aminoxyls, SDS of cas: 111865-47-5, the publication is Journal of Materials Chemistry (2001), 11(5), 1364-1369, database is CAplus.

The synthesis and magnetic properties of poly(2,2,4,4-tetramethyl-N-yloxy-1,4-dihydro-2H-3,1-benzoxazine-6,8-diyl-1,3-phenylene) (4) are described. Polyradical 4 was prepared by the Pd-catalyzed cross-coupling reaction of 6,8-dibromo-2,2,4,4-tetramethyl-1,4-dihydro-2H-3,1-benzoxazine and bis(trimethylene) 1,3-phenylenediboronate, followed by oxidation with m-chloroperoxybenzoic acid. The number average mol. weights of 4 determined by SEC (size exclusion chromatog.) were ∼4120 (15 repeating units), and the spin concentrations determined by EPR were up to 0.75 spin per repeating unit. The EPR spectrum of 4 in a toluene glass matrix showed the ΔM_s = 2 forbidden transition at g = 4.0. A Curie plot of the ΔM_s = 2 signal intensity vs. 1/T gave a straight line, suggesting that the polyradical is in a triplet ground state or a nearly degenerate singlet-triplet state.

Journal of Materials Chemistry published new progress about 111865-47-5. 111865-47-5 belongs to bromides-buliding-blocks, auxiliary class Benzenes, name is Mono(N,N,N-trimethyl-1-phenylmethanaminium) tribromide, and the molecular formula is C10H16Br3N, SDS of cas: 111865-47-5.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Kamachi, Hiroaki published the artcileStructure-activity studies on the side chain of a simplified analog of aplysiatoxin (aplog-1) with anti-proliferative activity, Synthetic Route of 111865-47-5, the publication is Bioorganic & Medicinal Chemistry (2013), 21(10), 2695-2702, database is CAplus and MEDLINE.

We have recently developed a simplified analog of aplysiatoxin (aplog-1) as an activator of protein kinase C (PKC) with anti-proliferative activity like bryostatin 1. To identify sites in aplog-1 that could be readily modified to optimize therapeutic performance and to develop a mol. probe for examining the analog’s mode of action, substituent effects on the phenol ring were systematically examined Whereas hydrophilic acetamido derivatives were less active than aplog-1 in inhibiting cancer cell growth and binding to PKCδ, introduction of hydrophobic bromine and iodine atoms enhanced both biol. activities. The anti-proliferative activity was found to correlate closely with mol. hydrophobicity, and maximal activity was observed at a log P value of 4.0-4.5. An induction test with Epstein-Barr virus early antigen demonstrated that these derivatives have less tumor-promoting activity in vitro than aplog-1 regardless of the hydrophobicity of their substituents. These results would facilitate rapid preparation of mol. probes to examine the mechanism of the unique biol. activities of aplog-1.

Bioorganic & Medicinal Chemistry published new progress about 111865-47-5. 111865-47-5 belongs to bromides-buliding-blocks, auxiliary class Benzenes, name is Mono(N,N,N-trimethyl-1-phenylmethanaminium) tribromide, and the molecular formula is C10H16Br3N, Synthetic Route of 111865-47-5.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Oka, Hiroyuki published the artcileSynthesis and characterization of poly(1,3-phenylene)-based polyradical carrying cyclic nitroxides observation of ferromagnetic interaction, HPLC of Formula: 111865-47-5, the publication is Polymer Journal (Tokyo) (1999), 31(11-1), 979-982, database is CAplus.

A poly(1,3-phenylene) containing cyclic nitroxide radicals which are planar in most cases, favoring extensive delocalization of unpaired electrons over the whole of radical mol. was prepared and the magnetic properties were studied. The radical containing polyphenylene was prepared by Pd-catalyzed cross-coupling of 6,8-Dibromo-2,2,4,4-tetramethyl-1H,2H,4H-3,1-benzoxazine and 2,2′-(1,3-phenylene)bis-1,3,2-Dioxaborinane, in the presence of Bu₄NCl and K₂CO₃ under N; the intermediate was oxidized by 3-chloroperoxybenzoic acid to generate the polyradical. The spin concentration of the polyradical determined by ESR was 1.61 x 1021 spins/g, corresponding to 0.75 spin per repeating unit. Spin concentration was constant in the solid state for a long time at room temperature A clear absorption peak due to the AM^s = 2 forbidden transition was observed at 5.5-60 K. The signal intensity vs. T-1 plots gives a linear relationship, indicating that the polyradical is in part at least in a triplet ground state (or both the triplet and singlet are nearly degenerated). The intramol. magnetic interaction through the n-conjugation is thus ferromagnetic.

Polymer Journal (Tokyo) published new progress about 111865-47-5. 111865-47-5 belongs to bromides-buliding-blocks, auxiliary class Benzenes, name is Mono(N,N,N-trimethyl-1-phenylmethanaminium) tribromide, and the molecular formula is C10H16Br3N, HPLC of Formula: 111865-47-5.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Kakinami, Takaaki published the artcileHalogenation using quaternary ammonium polyhalides. XX. Bromination of phenols with polymer-bound benzyltrimethylammonium tribromide, Synthetic Route of 111865-47-5, the publication is Bulletin of the Chemical Society of Japan (1989), 62(10), 3373-5, database is CAplus.

Bromo-substituted phenols were obtained quant. by passing a solution of phenols in dichloromethane-methanol through a column packed with styrene polymer-bound benzyltrimethylammonium tribromide. Yields were 91-99%.

Bulletin of the Chemical Society of Japan published new progress about 111865-47-5. 111865-47-5 belongs to bromides-buliding-blocks, auxiliary class Benzenes, name is Mono(N,N,N-trimethyl-1-phenylmethanaminium) tribromide, and the molecular formula is C10H16Br3N, Synthetic Route of 111865-47-5.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Ding, Jiafeng published the artcileSynthesis, purification and characterization of several typical polybrominated diphenyl ethers (PBDEs) and polybrominated biphenyls (PBBs), Related Products of bromides-buliding-blocks, the publication is Huanjing Huaxue (2015), 34(7), 1377-1379, database is CAplus.

Several typical polybrominated di-Ph ethers (PBDEs), e. g., I, and polybrominated biphenyls (PBBs), e. g., II were synthesized by using coupling, oxidation and bromination, purified by using C18 semi-preparation HPLC, and then identified by using gas chromatog.-mass spectrometry (GC-MS) and ¹H-NMR (NMR). The results showed that the prepared products were consistent with the target products, with the purity over 99%.

Huanjing Huaxue published new progress about 111865-47-5. 111865-47-5 belongs to bromides-buliding-blocks, auxiliary class Benzenes, name is Mono(N,N,N-trimethyl-1-phenylmethanaminium) tribromide, and the molecular formula is C10H16Br3N, Related Products of bromides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Krishnananthan, Subramaniam published the artcileRegioselective Synthesis of Substituted 4-Alkylamino and 4-Arylaminophthalazin-1(2H)-ones, Product Details of C10H16Br3N, the publication is Journal of Organic Chemistry (2016), 81(4), 1520-1526, database is CAplus and MEDLINE.

An efficient regioselective synthesis of substituted 4-alkylamino and 4-arylaminophthalazin-1(1H)-ones 5 is described. This new method features the formation of substituted phthalazin-1(1H)-ones 3 by the reaction of 2-formylbenzoic acids 1 or 3-hydroxyisobenzofuran-1(3H)-ones 2 with hydrazine to generate phthalazin-1(2H)-ones 3. Subsequent regioselective bromination of phthalazin-1(2H)-ones 3 with benzyltrimethylammonium tribromide (BTMA-Br₃) followed by mixed copper-copper oxide-catalyzed amination of 4-bromophthalazin-1(2H)-ones 4 with primary amines generates aminophthalazin-1(2H)-ones in good overall yields.

Journal of Organic Chemistry published new progress about 111865-47-5. 111865-47-5 belongs to bromides-buliding-blocks, auxiliary class Benzenes, name is Mono(N,N,N-trimethyl-1-phenylmethanaminium) tribromide, and the molecular formula is C10H16Br3N, Product Details of C10H16Br3N.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Kakinami, Takaaki published the artcileHalogenation using quaternary ammonium polyhalides. XXV. Bromination of acetanilides with benzyltrimethylammonium tribromide-zinc chloride system, Formula: C10H16Br3N, the publication is Nippon Kagaku Kaishi (1990), 705-8, database is CAplus.

The reaction of acetanilides with equimolar amounts of PhCH₂N⁺Me₃ Br₃^– and ZnCl₂ in AcOH under mild conditions gave the bromo-substituted acetanilides in good yields. E.g., AcNHC₆H₃Me₂-3,5 gave 99% AcNHC₆HBr₂Me₂-2,4,3,5.

Nippon Kagaku Kaishi published new progress about 111865-47-5. 111865-47-5 belongs to bromides-buliding-blocks, auxiliary class Benzenes, name is Mono(N,N,N-trimethyl-1-phenylmethanaminium) tribromide, and the molecular formula is C10H16Br3N, Formula: C10H16Br3N.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Miura, Yozo published the artcileSyntheses and Characterization of Poly(1,3-phenylene-2-amino-1,3-phenylene)s and Dimer and Tetramer Model Compounds, HPLC of Formula: 111865-47-5, the publication is Macromolecules (1998), 31(7), 2041-2046, database is CAplus.

The Pd-catalyzed cross-coupling polycondensation of 2,6-dibromoaniline or 2,6-dibromo-4-tert-butylaniline with 1,3-phenylenebis(trimethylene boronate) in benzene-water in the presence of K₂CO₃ and Bu₄NCl gave poly(1,3-phenylene-2-amino-1,3-phenylene)s in 56-86% yields. The number average mol. weights of the poly(1,3-phenylene)s determined by GPC using styrene standards are 2500-5720, which correspond to the d.p. of 15.0-25.6. The thermal stabilities of the polyphenylenes were evaluated by thermal gravimetry. The corresponding dimer and tetramer model compounds of poly(1,3-phenylene-2-amino-1,3-phenylene)s were prepared, and their properties were compared with those of the poly(1,3-phenylene)s.

Macromolecules published new progress about 111865-47-5. 111865-47-5 belongs to bromides-buliding-blocks, auxiliary class Benzenes, name is Mono(N,N,N-trimethyl-1-phenylmethanaminium) tribromide, and the molecular formula is C10H16Br3N, HPLC of Formula: 111865-47-5.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary