Category: 1036461-93-4

Wu, Qiong published the artcilePoly[n]catenanes: Synthesis of molecular interlocked chains, Computed Properties of 1036461-93-4, the publication is Science (Washington, DC, United States) (2017), 358(6369), 1434-1439, database is CAplus and MEDLINE.

As the macromol. version of mech. interlocked mols., mech. interlocked polymers are promising candidates for the creation of sophisticated mol. machines and smart soft materials. Poly[n]catenanes, where the mol. chains consist solely of interlocked macrocycles, contain one of the highest concentrations of topol. bonds. We report, herein, a synthetic approach toward this distinctive polymer architecture in high yield (∼75%) via efficient ring closing of rationally designed metallosupramol. polymers. Light-scattering, mass spectrometric, and NMR characterization of fractionated samples support assignment of the high-molar mass product (number-average molar mass ∼21.4 kg per mol) to a mixture of linear poly[7-26]catenanes, branched poly[13-130]catenanes, and cyclic poly[4-7]catenanes. Increased hydrodynamic radius (in solution) and glass transition temperature (in bulk materials) were observed upon metalation with Zn²⁺.

Science (Washington, DC, United States) published new progress about 1036461-93-4. 1036461-93-4 belongs to bromides-buliding-blocks, auxiliary class Benzenes, name is 4-Bromo-N-butyl-2-nitroaniline, and the molecular formula is C15H24S, Computed Properties of 1036461-93-4.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

McKenzie, Blayne M. published the artcileMetallo-Responsive Liquid Crystalline Monomers and Polymers, Application In Synthesis of 1036461-93-4, the publication is Chemistry of Materials (2011), 23(15), 3525-3533, database is CAplus.

A series of liquid crystalline ligand-containing monomers with chemo-responsive properties was prepared and studied. These mols. are functionalized derivatives of the 2,6-bisbenzimidazolylpyridine (Bip) ligand. Tailoring the size of the aromatic core and the length of two pairs of alkyl substituents allows the preparation of mesogens with a range of tunable thermal liquid crystalline transitions and phases. The binding of lanthanide- and/or transition metal salts to the ligand containing mesogens results in a transition from a liquid crystalline to an isotropic state. Acyclic diene metathesis of the monomers yielded either oligomers or polymers, dictated by whether the alkene is either terminal or nonterminal, resp. Both oligomers and polymers exhibit enantiotropic liquid crystalline behavior and become isotropic in the presence of metal ions.

Chemistry of Materials published new progress about 1036461-93-4. 1036461-93-4 belongs to bromides-buliding-blocks, auxiliary class Benzenes, name is 4-Bromo-N-butyl-2-nitroaniline, and the molecular formula is C10H13BrN2O2, Application In Synthesis of 1036461-93-4.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Guo, Pu published the artcileCompound shape effects in minor groove binding affinity and specificity for mixed sequence DNA, Name: 4-Bromo-N-butyl-2-nitroaniline, the publication is Journal of the American Chemical Society (2018), 140(44), 14761-14769, database is CAplus and MEDLINE.

AT-specific heterocyclic cations that bind in the DNA duplex minor groove have had major successes as cell and nuclear stains and as therapeutic agents which can effectively enter human cells. Expanding the DNA sequence recognition capability of the minor groove compounds could also expand their therapeutic targets and have an impact in many areas, such as modulation of transcription factor biol. activity. 2268681509. Success in the design of mixed sequence binding compounds has been achieved with N-methylbenzimidazole (N-MeBI) thiophenes which are preorganized to fit the shape of the DNA minor groove and H-bond to the -NH of G·C base pairs that projects into the minor groove. Initial compounds bound strongly to a single G·C base pair in an AT context with a specificity ratio of 50 (K_d AT-GC/K_d AT) or less and this was somewhat low for biol. use. We felt that modifications of compound shape could be used to probe local DNA microstructure in target mixed base-pair sequences of DNA and potentially improve the compound binding selectivity. Modifications were made by increasing the size of the benzimidazole N-substituent, e.g., by using N-iso-Bu instead of N-Me, and by changing the mol. twist by introducing substitutions at specific positions on the aromatic core of the compounds In both cases, we were able to achieve a dramatic increase in binding specificity, including no detectable binding to pure AT sequences, without a significant loss in affinity to mixed base-pair target sequences.

Journal of the American Chemical Society published new progress about 1036461-93-4. 1036461-93-4 belongs to bromides-buliding-blocks, auxiliary class Benzenes, name is 4-Bromo-N-butyl-2-nitroaniline, and the molecular formula is C10H13BrN2O2, Name: 4-Bromo-N-butyl-2-nitroaniline.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary