Organic bromides such as alkyl bromides are used as fumigants in agriculture to control insects. 5392-10-9, formula is C9H9BrO3, Name is 2-Bromo-4,5-dimethoxybenzaldehyde. Ethylene bromide is one of the commercially important organic bromides which are the component of leaded gasoline. Recommanded Product: 2-Bromo-4,5-dimethoxybenzaldehyde.
Xiao, You-Cai;Chen, Xiao-Pan;Deng, Ji;Yan, Yu-Hang;Zhu, Kai-Rong;Li, Gen;Yu, Jun-Lin;Brem, Jurgen;Chen, Fener;Schofield, Christopher J.;Li, Guo-Bo research published 《 Design and enantioselective synthesis of 3-(α-acrylic acid) benzoxaboroles to combat carbapenemase resistance》, the research content is summarized as follows. Chiral 3-acrylate-substituted 5-R1-6-R2-benzoxaboroles (4-l, R1, R2 = H, F, Cl, OMe, OEt, OiPr) were designed as carbapenemase inhibitors and efficiently synthesized via asym. Morita-Baylis-Hillman reaction. Some of the benzoxaboroles were potent inhibitors of clin. relevant carbapenemases and restored the activity of meropenem in bacteria harbouring these enzymes. Crystallog. analyses validate the proposed mechanism of binding to carbapenemases, i.e. in a manner relating to their antibiotic substrates. The results illustrate how combining a structure-based design approach with asym. catalysis can efficiently lead to potent β-lactamase inhibitors and provide a starting point to develop drugs combating carbapenemases.
Recommanded Product: 2-Bromo-4,5-dimethoxybenzaldehyde, 2-Bromo-4,5-dimethoxybenzaldehyde is a useful research compound. Its molecular formula is C9H9BrO3 and its molecular weight is 245.07 g/mol. The purity is usually 95%.
2-Bromo-4,5-dimethoxybenzaldehyde is a synthetic compound that has been shown to be an effective agent for inducing apoptosis in leukemia cells. It is an efficient method for synthesizing the compound and ha2-Bromo-4,5-dimethoxybenzaldehyde induces cell death by topoisomerase-mediated DNA cleavage, which results in chromosomal fragmentation and high levels of reactive oxygen species in the cell., 5392-10-9.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary