Application of 3814-30-0, The chemical industry reduces the impact on the environment during synthesis 3814-30-0, name is (Bromomethyl)cyclopentane, I believe this compound will play a more active role in future production and life.
General procedure: To a stirred solution of ethyl 2-(4-aminophenoxy)-2-methylpropanoate 12 (1 equiv) and anhydrous potassium carbonate(0.5 equiv) in dry DMF was slowly added the corresponding alkyl bromides (1 equiv), and then heated to 80 C until the reaction completed. The mixture was added ethyl acetate and washed with water and brine successively, dried, filtered and concentrated under reduced pressure. The residue was purified by column chromatography.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, (Bromomethyl)cyclopentane, other downstream synthetic routes, hurry up and to see.
Reference:
Article; Li, Yongqiang; Tian, Kang; Qin, Aifang; Zhang, Lijian; Huo, Lianchao; Lei, Lei; Shen, Zhufang; Song, Hongrui; Feng, Zhiqiang; European Journal of Medicinal Chemistry; vol. 76; (2014); p. 182 – 192;,
Bromide – Wikipedia,
bromide – Wiktionary