Organic bromides such as alkyl bromides are used as fumigants in agriculture to control insects. 244205-40-1, formula is C6H6BBrO2, Name is (2-Bromophenyl)boronic acid. Ethylene bromide is one of the commercially important organic bromides which are the component of leaded gasoline. Application of C6H6BBrO2.
Liu, Haidong;Xing, Renyi;Ren, Kewei;Xue, Fei;Feng, Chao research published 《 α-Iminyl Cation-Involved Indole Construction via Bronsted Acid Promoted Reaction of Isoxazol-5-ones》, the research content is summarized as follows. Herein, a strategically novel method for the efficient construction of indole skeletons I (R1 = Ph, furan-2-yl, cyclohexyl, etc.; R2 = H, Me, C(O)OH; R1R2 = -((CH2)4)-; R3 = 5-Me, 7-Cl, 4-Br, etc.) using 2-phenylisoxazol-5-ones II (R4 = H, 4-Ph, 2-Me, 3,4-Cl2, etc.) as the starting material was reported. This reaction proceeds via Bronsted acid promoted α-iminyl cation generation by N-O bond cleavage and a subsequent intramol. cyclization to obtain 1H-indole-3-carboxylic acids III, which further undergoes decarboxylation to afford the final product. Control experiments show that the N-O bond cleavage and intramol. cyclization proceeds so fast that the 1H-indole-3-carboxylic acids III, could be isolated in high yields even after 5-10 min. The substrate scope of this transformation is broad and the desired products are obtained in moderate to good yields. The transition-metal-free reaction condition, CO2 as the sole byproduct, and good practicability adds synthetic potential of this transformation in pharmaceuticals and flavors industry.
244205-40-1, 2-Bromophenylboronic Acid is used as an inhibitor of the hormone sensitive lipase.
2-Bromophenylboronic acid, also known as 2-Bromophenylboronic acid, is a useful research compound. Its molecular formula is C6H6BBrO2 and its molecular weight is 200.83 g/mol. The purity is usually 95%.
2-Bromophenylboronic acid is a glucose monitoring agent that has a ruthenium complex with an acidic environment. The nitro group and the amines are in close proximity to the boron center, and this proximity leads to a high nucleophilic character of the molecule. This reactivity allows 2-bromophenylboronic acid to be used as a fluorescence probe for acidic environments. 2-Bromophenylboronic acid also inhibits secretase enzymes, which are involved in Alzheimer’s disease and other neurodegenerative disorders. It is an inhibitor of γ-secretase, which is responsible for cleaving the amyloid precursor protein (APP), and it has shown efficacy against biphenyl, an anticancer drug that binds to benzodiazepine receptors. 2-Bromophenylboronic acid is also an enantiopure compound because all four substituents are different from each other., Application of C6H6BBrO2
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary