Pandiri, Madhuri; Nukala, Satheesh Kumar; Dasari, Gouthami; Badithapuram, Vinitha; Bandari, Srinivas published an article in 2021. The article was titled 《Design and Synthesis of Some New N-Phenyl-[1,2,4]triazolo[4,3-a]quinoxaline-1-sulfonamide Derivatives and Their Anti-Cancer Activity》, and you may find the article in Russian Journal of General Chemistry.Recommanded Product: 626-40-4 The information in the text is summarized as follows:
Synthesis of some new derivatives of N-phenyl-[1,2,4]triazolo[4,3-a]quinoxaline-1-sulfonamide and their in vitro anticancer activity on four human cancer lines like MCF-7 (human breast cancer cell line), HeLa (human cervical cancer cell line), A549 (human lung cancer cell line), and IMR32 (human neuroblastoma cell line) have been studied. Among the products, N-(3,5-dichloronitrophenyl)-[1,2,4]triazolo[4,3-a]quinoxaline-1-sulfonamide, is characterized by the activity higher than the standard Etoposide against the tested cancer cell lines. In the experiment, the researchers used many compounds, for example, 3,5-Dibromoaniline(cas: 626-40-4Recommanded Product: 626-40-4)
3,5-Dibromoaniline(cas: 626-40-4) belongs to anime. Reaction with nitrous acid (HNO2), which functions as an acylating agent that is a source of the nitrosyl group (―NO), converts aliphatic primary amines to nitrogen and mixtures of alkenes and alcohols corresponding to the alkyl group in a complex process. This reaction has been used for analytical determination of primary amino groups in a procedure known as the Van Slyke method.Recommanded Product: 626-40-4
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary