《SO4-2/SnO2-catalyzed cyclocondensation for the synthesis of fully functionalized pyridines》 was published in Journal of Heterocyclic Chemistry in 2020. These research results belong to Koduri, Ramesh Goud; Pagadala, Ramakanth; Boodida, Sathyanarayana; Varala, Ravi. SDS of cas: 6630-33-7 The article mentions the following:
An efficient and promising synthetic approach to assemble skeletons of multifunctionalized pyridine derivatives I [R = H, 4-Br, 2-Cl, 2-OMe, etc.; R1 = R2 = Me; R1R2 = -(CH2)5-] in presence of recyclable heterogeneous sulfated tin oxide (STO) catalyst has been evolved. The STO catalyst was used as a promoter for the cyclocondensation process in ethanol at 70°C. Overall performance of this catalyst was attributed to the cooperative contribution of its Lewis and Bronsted-Lowry acidic sites. Nanosized STO catalyst was synthesized by using sol-gel process and characterized by Fourier transform IR (FTIR) spectroscopy, X-ray diffraction (XRD), 1H-NMR, and SEM (SEM). This catalyst tolerates most of the substrates, and the protocol shows precious capabilities consisting of high yields, operational simplicity, less reaction time, and eco-friendly conditions. The newly synthesized heterogeneous catalyst was easily separated and reused. All the reactions are carried out for subsequent cycles without significant loss of catalytic activity and with good proficiency. In addition to this study using o-Bromobenzaldehyde, there are many other studies that have used o-Bromobenzaldehyde(cas: 6630-33-7SDS of cas: 6630-33-7) was used in this study.
o-Bromobenzaldehyde(cas: 6630-33-7) is used in L-threonine aldolase-catalyzed enantio/diastereoselective aldol reactions.SDS of cas: 6630-33-7It is a key starting material in the total synthesis of an anticancer agent, (-)-taxol.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary