《Cobalt(II)-Catalyzed Stereoselective Olefin Isomerization: Facile Access to Acyclic Trisubstituted Alkenes》 was published in Journal of the American Chemical Society in 2020. These research results belong to Zhang, Sheng; Bedi, Deepika; Cheng, Lu; Unruh, Daniel K.; Li, Guigen; Findlater, Michael. SDS of cas: 1779-49-3 The article mentions the following:
Stereoselective synthesis of trisubstituted alkenes is a long-standing challenge in organic chem., due to the small energy differences between E and Z isomers of trisubstituted alkenes (compared with 1,2-disubstituted alkenes). Transition metal-catalyzed isomerization of 1,1-disubstituted alkenes can serve as an alternative approach to trisubstituted alkenes, but it remains underdeveloped owing to issues relating to reaction efficiency and stereoselectivity. Here we show that a novel cobalt catalyst can overcome these challenges to provide an efficient and stereoselective access to a broad range of trisubstituted alkenes. This protocol is compatible with both mono- and dienes and exhibits a good functional group tolerance and scalability. Moreover, it has proven to be a useful tool to construct organic luminophores and a deuterated trisubstituted alkene. A preliminary study of the mechanism suggests that a cobalt-hydride pathway is involved in the reaction. The high stereoselectivity of the reaction is attributed to both a π-π stacking effect and the steric hindrance between substrate and catalyst. After reading the article, we found that the author used Methyltriphenylphosphonium bromide(cas: 1779-49-3SDS of cas: 1779-49-3)
Methyltriphenylphosphonium bromide(cas: 1779-49-3) is an organophosphorus compound, with potential use as a precursor and a solvent in organic synthesis. And it is used widely for methylenation via the Wittig reaction.SDS of cas: 1779-49-3
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary