Chen, Lian-Mei; Zhou, Chuang; Li, Jing; Li, Jun; Guo, Xiao-Qiang; Kang, Tai-Ran published the artcile< Copper-catalyzed reactions of α,β-unsaturated N-tosylhydrazones with diaryliodonium salts to construct N-arylpyrazoles and diaryl sulfones>, Name: 3-(4-Bromophenyl)acrylaldehyde, the main research area is propenyl tosylhydrazone diaryliiodonium triflate copper catalyst tandem heterocyclization Ullman; arylpyrazole diarylsulfone preparation regioselective.
An economical copper-catalyzed reaction of α,β-unsaturated N-tosylhydrazones with diaryliodonium salts to construct both N-arylpyrazoles and diaryl sulfones was developed. Both the p-toluenesulfonyl anion and the 3-arylpyrazole intermediates were formed in-situ from N-tosylhydrazones. Subsequently, the former reacted rapidly with diaryliodonium salts to give diaryl sulfones and aryl iodide intermediates and the latter reacted with aryl iodide to give N-arylpyrazoles under copper-catalyzed conditions. Using unsym. mesityl phenyliodonium salts as substrates, mesityl p-toluenesulfide was obtained as the major product. This reaction took full advantage of the “”waste”” part of substrates to form an extra diaryl sulfone.
Organic & Biomolecular Chemistry published new progress about Aromatic compounds, sulfones Role: PRP (Properties), RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 3893-18-3 belongs to class bromides-buliding-blocks, and the molecular formula is C9H7BrO, Name: 3-(4-Bromophenyl)acrylaldehyde.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary