Chen, Ziren; Xue, Fei; Zhang, Yonghong; Jin, Weiwei; Wang, Bin; Xia, Yu; Xie, Mengwei; Abdukader, Ablimit; Liu, Chenjiang published the artcile< Visible-Light-Promoted [3 + 2] Cyclization of Chalcones with 2-Mercaptobenzimidazoles: A Protocol for the Synthesis of Imidazo[2,1-b]thiazoles>, Name: 3-(4-Bromophenyl)acrylaldehyde, the main research area is imidazothiazole preparation photochem; chalcone mercaptobenzimidazole heterocyclization.
A visible-light-promoted [3+2] cyclization between chalcones R 1CH=CHC(O)R2 (R1 = Ph, thiophen-2-yl, naphthalen-2-yl, etc.; R2 = H, Ph, thiophen-2-yl, naphthalen-1-yl, etc.) and 2-mercaptobenzoimidazoles I (R3 = R4 = H, Me, OMe, Cl) for the construction of diverse imidazo[2,1-b]thiazoles II and III, IV via an electron-donor-acceptor (EDA) complex has been developed. This novel aminothiolation can be realized under only visible light irradiation without the aid of external photocatalysts, transition metals, and oxidants. Mechanistic investigations have revealed that the thiol anions and chalcones form EDA complexes, providing a novel strategy for the synthesis of imidazo[2,1-b]thiazoles II, III, and IV.
Organic Letters published new progress about Benzimidazoles Role: RCT (Reactant), RACT (Reactant or Reagent). 3893-18-3 belongs to class bromides-buliding-blocks, and the molecular formula is C9H7BrO, Name: 3-(4-Bromophenyl)acrylaldehyde.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary