Lathrop, Stephen P.; Rovis, Tomislav published the artcile< Asymmetric Synthesis of Functionalized Cyclopentanones via a Multicatalytic Secondary Amine/N-Heterocyclic Carbene Catalyzed Cascade Sequence>, Formula: C9H7BrO, the main research area is alkyl aryl enal dicarbonyl diketone ketoester secondary amine addition; heterocyclic carbene intramol diastereoselective regioselective enantioselective crossed benzoin; cyclopentanone stereoselective preparation.
A one-pot, asym. multi-catalytic formal [3+2] reaction between 1,3-dicarbonyls and α,β-unsaturated aldehydes is described. The multi-catalytic process involves a secondary amine catalyzed Michael addition followed by a N-heterocyclic carbene catalyzed intramol. crossed benzoin reaction to afford densely functionalized cyclopentanones with high enantioselectivities. The reaction proceeds with a variety of alkyl and aryl enals as well as a range of 1,3-dicarbonyls (diketones and β-ketoesters). The functionalized products are obtained from cheap, readily available starting materials in a rapid and efficient manner in a one-pot, one-step operation.
Journal of the American Chemical Society published new progress about 1,3-Dicarbonyl compounds Role: RCT (Reactant), RACT (Reactant or Reagent). 3893-18-3 belongs to class bromides-buliding-blocks, and the molecular formula is C9H7BrO, Formula: C9H7BrO.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary