Qi, Zhi-Chao; Lou, Qin-Xin; Niu, Yuan; Yang, Shang-Dong published their research in Chemical Communications (Cambridge, United Kingdom) in 2021. The article was titled 《Temporary (P=O) directing group enabled carbazole ortho arylation via palladium catalysis》.Reference of 3,6-Dibromo-9H-carbazole The article contains the following contents:
A palladium-catalyzed, temporary P(O) directing group assisted C-H bond arylation of carbazoles was achieved. The release of the directing group occurred spontaneously in the reaction and the mechanistic studies indicated that acid was essential for N-P bond cleavage. The experimental part of the paper was very detailed, including the reaction process of 3,6-Dibromo-9H-carbazole(cas: 6825-20-3Reference of 3,6-Dibromo-9H-carbazole)
3,6-Dibromo-9H-carbazole(cas: 6825-20-3) is used as a pharmaceutical intermediate, and also an important intermediate of synthesizing optoelectronic materials. It has been used as a reagent in the synthesis of P7C3-A20 which is a potent neuroprotective agent.Reference of 3,6-Dibromo-9H-carbazole
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary