Bera, Sourav Sekhar; Bahukhandi, Srishti Ballabh; Empel, Claire; Koenigs, Rene M. published their research in Chemical Communications (Cambridge, United Kingdom) in 2021. The article was titled 《Catalyst-controlled site-selective N-H and C3-arylation of carbazole via carbene transfer reactions》.Application In Synthesis of 3,6-Dibromo-9H-carbazole The article contains the following contents:
A site-selective direct arylation reaction of carbazole and other N-heterocycles with diazo-naphthalen-2(1H)-ones was developed. While Au(I)-NHC catalysts led to selective C3-arylation, palladium acetate allowed for selective N-H arylation, displaying complete site-selectivity each. To show the applicability of these arylation reactions, one-pot, two-fold diarylation reactions of carbazole were demonstrated. In the experiment, the researchers used 3,6-Dibromo-9H-carbazole(cas: 6825-20-3Application In Synthesis of 3,6-Dibromo-9H-carbazole)
3,6-Dibromo-9H-carbazole(cas: 6825-20-3) is used as a reagent in the synthesis of P7C3-A20 which is a potent neuroprotective agent. And it has been used in the preparation of N-(2-hydroxyethyl)-3,6-dibromocarbazole.Application In Synthesis of 3,6-Dibromo-9H-carbazole
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary