Garcia-Rodriguez, Jose; Mendiratta, Saurabh; White, Michael A.; Xie, Xiao-Song; De Brabander, Jef K. published the artcile< Synthesis and structure-activity studies of the V-ATPase inhibitor saliphenylhalamide (SaliPhe) and simplified analogs>, HPLC of Formula: 6942-39-8, the main research area is salicylihalamide synthesis anticancer antiviral structure activity relationship; VATPase inhibitor salicylihalamide analog preparation; Anticancer; Antiviral; Benzolactone; Salicylihalamide; V-ATPase.
An efficient total synthesis of the potent V-ATPase inhibitor saliphenylhalamide (SaliPhe), a synthetic variant of the natural product salicylihalamide A (SaliA), has been accomplished aimed at facilitating the development of SaliPhe as an anticancer and antiviral agent. This new approach enabled facile access to derivatives for structure-activity relationship studies, leading to simplified analogs that maintain SaliPhe’s biol. properties. These studies will provide a solid foundation for the continued evaluation of SaliPhe and analogs as potential anticancer and antiviral agents.
Bioorganic & Medicinal Chemistry Letters published new progress about Antitumor agents. 6942-39-8 belongs to class bromides-buliding-blocks, and the molecular formula is C8H6BrFO2, HPLC of Formula: 6942-39-8.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary