Zeng, Dishu; Yang, Tianbao; Tang, Niu; Deng, Wei; Xiang, Jiannan; Yin, Shuang-Feng; Kambe, Nobuaki; Qiu, Renhua published the artcile< UV-Light-Induced Dehydrogenative N-Acylation of Amines with 2-Nitrobenzaldehydes To Give 2-Aminobenzamides>, Quality Control of 3959-07-7, the main research area is aminobenzamide green preparation; amine ortho nitrobenzaldehyde visible light induced dehydrogenative acylation; quinazolinone preparation; beta keto carboxylic acid aminobenzamide cyclization.
Green and efficient method for the synthesis of aminobenzamides ArC(O)NHR [Ar = 2-H2NPh, 2-H2N-4-MeC6H4, 2-H2N-4-ClC6H4, etc.; R = Ph, Cy, n-Bu, etc.] via UV-light-induced dehydrogenative N-acylation of amines with o-nitrobenzaldehydes was reported. The reaction was also readily achieved on a gram scale. The utility of the 2-aminobenzamide building block in organic synthesis was shown by their use in the preparation of quinazolinone derivatives The method was applied to amino acid derivatives as the amine component, which smoothly gave N-(2-aminobenzoyl)acetate derivatives at room temperature Finally, a plausible mechanism was proposed.
Synthesis published new progress about Amines Role: RCT (Reactant), RACT (Reactant or Reagent). 3959-07-7 belongs to class bromides-buliding-blocks, and the molecular formula is C7H8BrN, Quality Control of 3959-07-7.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary