Companyo, Xavier; Alba, Andrea-Nekane; Cardenas, Francisco; Moyano, Albert; Rios, Ramon published the artcile< Asymmetric Organocatalytic Cyclopropanation - Highly Stereocontrolled Synthesis of Chiral Cyclopropanes with Quaternary Stereocenters>, SDS of cas: 3893-18-3, the main research area is unsaturated aldehyde bromo keto ester chiral silyloxymethylpyrrolidine asym cyclopropanation; cyclopropane carboxaldehyde derivative stereoselective preparation; chiral silyloxymethylpyrrolidine asym cyclopropanation organocatalyst.
A convenient and novel domino reaction for the synthesis of highly functionalized cyclopropanes is reported. The addition of 2-bromo keto esters to a variety of α,β-unsaturated aldehydes catalyzed by secondary amines leads to chiral cyclopropanes, e.g., I, with three stereogenic carbon atoms, including one quaternary stereocenter, in a highly stereocontrolled fashion.
European Journal of Organic Chemistry published new progress about Cycloalkanes Role: SPN (Synthetic Preparation), PREP (Preparation). 3893-18-3 belongs to class bromides-buliding-blocks, and the molecular formula is C9H7BrO, SDS of cas: 3893-18-3.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary