《Enzyme activity of thiophene-fluorene based-copolymer blended with urease in thin films》 was published in Colloids and Surfaces, A: Physicochemical and Engineering Aspects in 2020. These research results belong to Rodrigues, Rebeca da Rocha; de Aquino, Tamires Pedrali; Caseli, Luciano; Peres, Laura Oliveira. Name: 2,5-Dibromothiophene The article mentions the following:
Enzyme activity can be boosted if the mol. architecture of films is manipulated. In this paper, we show an alternative way to immobilize the enzyme urease in a matrix composed of the copolymer poly[(9,9-dioctylfluorene)-co-thiophene] by using the spin coating method. The films were characterized with Fluorescence, UV-vis, and IR spectroscopies, confirming not only the adsorption of the enzyme, but also the maintenance of its secondary structure. Enzyme activity of the blended films was evaluated in terms of hydrolysis of urea as a heterogeneous catalyst. As measured with UV-vis spectroscopy, the blended films presented substrate-enzyme affinity in relation to the Langmuir-Blodgett method, which may be important for the production of enzymic sensors with enhanced performance. This increase was related to the configurational disorder in the copolymer/enzyme blend with their chains being intertwined, facilitating the access of urea to the catalytic site of the enzyme. The experimental part of the paper was very detailed, including the reaction process of 2,5-Dibromothiophene(cas: 3141-27-3Name: 2,5-Dibromothiophene)
2,5-Dibromothiophene(cas: 3141-27-3) , is mainly used as pharmaceutical intermediate and synthesis intermediate. 2,5-Dibromothiophene may be used in the preparation of soluble α,ω-diformyl-a-oligothiophenes.Name: 2,5-Dibromothiophene
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Bromide – Wikipedia,
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