Rotbergs, J.; Cema, G.; Oskaja, V. published the artcile< Condensation dicarboxylic acid anhydrides with compounds containing active methylene groups. V. 3-Bromophthalic anhydride condensation with some β-dicarbonyl compounds>, Computed Properties of 82-73-5, the main research area is INDANS VIA PHTHALIC ANHYDRIDE; BENZALINDANS VIA PHTHALIC ANHYDRIDE.
Condensation of 4.54 g. 3-bromophthalic anhydride (I) with 2.6 g. Et acetoacetate in 10 g. Ac2O and 4 g. Et3N at room temperature and treatment on the following day with 20 g. ice and 10 ml. concentrated HCl yielded 5.1 g. product, which after dissolving in a mixture of 750 ml. hot H2O and 150 ml. concentrated HCl gave 2.5 g. 4-bromoindan-1,3-dione (II), decomposed 158-9°; dioxime decomposed 285°. Boiling a mixture of 0.44 g. II, 0.21 g. BzH, 10 ml. EtOH, and 0.05 ml. piperidine gave, after addition of 0.2 ml. AcOH, 0.6 g. 4-bromo-2-benzalindan-1,3-dione, m. 144-6° (EtOH). Similarly prepared was 78% 4-bromo-2-(p-nitrobenzal)indan-1,3-dione, m. 283-4° (AcOH). Reaction of 2.27 g. I with 1 g. Ac2CH2, 5 g. Ac2O, and 1 g. Et3N for 24 hrs. gave 0.82 g. III, m. 165-6° (MeOH). Similarly were prepared: 41% IV (with BzCH2Ac), m. 182-3° (EtOH); 53% V (with Bz2CH2), m. 186-7° (EtOAc); 66% VI (with di-Et malonate), m. 126-7° (MeOH). Unlike the condensation product of I with Et acetoacetate, III-VI are stable when refluxed with dilute HCl.
Latvijas PSR Zinatnu Akademijas Vestis, Kimijas Serija published new progress about Carbonyl compounds (organic) Role: RCT (Reactant), RACT (Reactant or Reagent). 82-73-5 belongs to class bromides-buliding-blocks, and the molecular formula is C8H3BrO3, Computed Properties of 82-73-5.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary