Gopalaiah, Kovuru; Choudhary, Renu published the artcile< Synthesis of Krohnke pyridines through iron-catalyzed oxidative condensation/double alkynylation/amination cascade strategy>, Category: bromides-buliding-blocks, the main research area is arylacetylene arylmethylamine iron regioselective tandem oxidative condensation alkynylation amination; triarylpyridine preparation.
An efficient protocol for the synthesis of sym. and unsym. 2,4,6-trisubstituted pyridines via oxidative cascade annulation of arylacetylenes with benzylamines was developed. The reaction proceeded smoothly by utilizing iron(II) triflate as a catalyst and mol. oxygen as an oxidant with broad substrate scope. Mechanistic studies revealed that the reaction may experience an oxidative condensation followed by double alkynylation and amination process.
Tetrahedron published new progress about Alkynes, aryl Role: RCT (Reactant), RACT (Reactant or Reagent). 3959-07-7 belongs to class bromides-buliding-blocks, and the molecular formula is C7H8BrN, Category: bromides-buliding-blocks.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary