Zhang, Tiexin; Huang, Xian; Wu, Luling published the artcile< A Facile Synthesis of 2H-Chromenes and 9-Functionalized Phenanthrenes through Reactions between α,β-Unsaturated Compounds and Arynes>, Quality Control of 3893-18-3, the main research area is chromene preparation; phenanthrene preparation; annulation aryne unsaturated compound.
Facile syntheses of 2H-chromenes or 9-functionalized phenanthrenes under mild conditions in moderate to good yields have been developed. They each involve annulations of arynes with α,β-unsaturated compounds bearing different electron-withdrawing groups (EWGs). Depending on the natures of the different EWGs, the reactions proceed by different pathways: enals react with arynes through a tandem [2+2] cycloaddition/thermal electrocyclic ring-opening/6e-electrocyclization sequence to afford 2H-chromenes, whereas acyl-/ethoxycarbonyl-/cyano-substituted styrenes undergo Diels-Alder reactions with arynes followed by aromatization to afford 9-functionalized phenanthrenes. The scope, limitations, regioselectivities and mechanisms have been studied and are discussed in detail.
European Journal of Organic Chemistry published new progress about [2+2] Cycloaddition reaction. 3893-18-3 belongs to class bromides-buliding-blocks, and the molecular formula is C9H7BrO, Quality Control of 3893-18-3.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary