Organobromine compounds, also called organobromides, are organic compounds that contain carbon bonded to bromine. 4224-70-8, formula is C6H11BrO2, The most pervasive is the naturally produced bromomethane. Related Products of 4224-70-8
Choi, Peter J.;Cooper, Elizabeth A.;Park, Thomas I.-H.;Denny, William A.;Jose, Jiney research published 《 Novel synthetic approach for accessing drug-dye conjugates for targeted tumour therapy》, the research content is summarized as follows. The use of heptamethine cyanine dyes (HMCD) as a vehicle for targeted delivery of drugs to cancer tissues shows promise. The synthesis of drug-dye conjugates is hampered by scalability and purification issues. Herein we disclose synthetic procedure to procure such drug-dye conjugates that avoid the formation of undesired side products. This novel procedure also avoids the use of HPLC, thereby improving the yield and scalability of such drug-dye conjugates. Improving the atom-efficient coupling of drugs to HMCDs, will facilitate the clin. translation of HMCDs as a drug-delivery system for targeted tumor therapies.
Related Products of 4224-70-8, 6-bromohexanoic acid is an organobromine compound comprising hexanoic acid having a bromo substituent at the 6-position. It derives from a hexanoic acid.
6-Bromohexanoic acid is a useful research compound. Its molecular formula is C6H11BrO2 and its molecular weight is 195.05 g/mol. The purity is usually 95%.
6-Bromohexanoic acid is useful for the preparation of anti-CTLA4 compounds as antitumor agents.
6-Bromohexanoic acid is a fatty acid that has been shown to be an effective agent for the treatment of cancer. It is used in gene therapy to inhibit the growth of cancer cells by binding to and then activating transcription factors. 6-Bromohexanoic acid can also be used as a chemotherapeutic agent and has been shown to cause apoptosis in monoclonal antibody-treated cells. 6-Bromohexanoic acid has pharmacokinetic properties that are similar to those of other fatty acids. The reaction solution was found to have high chemical stability, which may be due to the presence of nitrogen atoms. This reaction solution was found to adsorb onto the surface of monoclonal antibodies and cell culture, altering their properties., 4224-70-8.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary