Organic compounds having carbon bonded to bromine are called organic bromides. 6911-87-1, formula is C7H8BrN, Name is 4-Bromo-N-methylaniline. Depending on the type of carbon to which the bromine is bonded, organic bromide could be alkyl, alkenyl, alkynyl, or aryl. Application of C7H8BrN.
Chen, Yong-Jia;Liu, Hua;Zhang, Shao-Yong;Li, Hu;Ma, Kun-Yuan;Liu, Ying-Qian;Yin, Xiao-Dan;Zhou, Rui;Yan, Yin-Fang;Wang, Ren-Xuan;He, Ying-Hui;Chu, Qing-Ru;Tang, Chen research published 《 Design, Synthesis, and Antifungal Evaluation of Cryptolepine Derivatives against Phytopathogenic Fungi》, the research content is summarized as follows. Inspired by the widely antiphytopathogenic application of diversified derivatives from natural sources, cryptolepine and its derivatives were subsequently designed, synthesized, and evaluated for their antifungal activities against four agriculturally important fungi Rhizoctonia solani, Botrytis cinerea, Fusarium graminearum, and Sclerotinia sclerotiorum. The results obtained from in vitro assay indicated that compounds showed great fungicidal property against B. cinerea (EC50 < 4μg/mL); especially, I presented significantly prominent inhibitory activity with an EC50 of 0.027μg/mL. In the pursuit of further expanding the antifungal spectrum of cryptolepine, ring-opened compound II produced better activity with an EC50 of 3.632μg/mL against R. solani and an EC50 of 5.599μg/mL against F. graminearum. Furthermore, I was selected to be a candidate to investigate its preliminary antifungal mechanism to B. cinerea, revealing that not only spore germination was effectively inhibited and the normal physiol. structure of mycelium was severely undermined but also detrimental reactive oxygen was obviously accumulated and the normal function of the nucleus was fairly disordered. Besides, in vivo curative experiment against B. cinerea found that the therapeutic action of I was comparable to that of the pos. control azoxystrobin. These results suggested that compound I could be regarded as a novel and promising agent against B. cinerea for its valuable potency.
6911-87-1, 4-Bromo-N-methylaniline is a aniline based compound known to exhibit mutagenic properties.
4-Bromo-N-methylaniline is a useful research compound. Its molecular formula is C7H8BrN and its molecular weight is 186.05 g/mol. The purity is usually 95%.
4-Bromophenylmethylamine is an organic compound that has anti-inflammatory properties and is used as a pharmaceutical. It belongs to the group of amines. The hydrolysis of 4-bromophenylmethylamine by hydrochloric acid produces phenol and bromamine (NHBr). The reaction system can be used to synthesize a number of compounds, including anilines, benzofurans, and other aromatic compounds. 4-Bromophenylmethylamine reacts with muscle tissue in a similar manner as acetaminophen does. This drug also has been shown to have significant effects on the energy metabolism in the muscles of rats that are given carbon source., Application of C7H8BrN
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary