Safety of 3,4,5-Trichloropyridine. The mechanism of aromatic electrophilic substitution of aromatic heterocycles is consistent with that of benzene. Compound: 3,4,5-Trichloropyridine, is researched, Molecular C5H2Cl3N, CAS is 33216-52-3, about Concise synthesis of N-phosphorylated amides through three-component reactions. Author is Zhu, Yuan-Yuan; Zhang, Tao; Zhou, Linlin; Yang, Shang-Dong.
N-Phosphorylated amides continue to be an unparalleled asset for the development of pharmaceutical mols., and the importance of this framework has inspired researchers to look for concise and efficient methods for the synthesis of this unit. In this work, a new strategy was developed in which a one-pot synthesis of N-phosphorylated amides was achieved by a three-component reaction with carboxylic acids, phosphorus chlorides and azides under mild reaction conditions. To authors knowledge, this is the first study in which this framework was constructed through a multicomponent reaction, which is innovative, efficient and economical.
In addition to the literature in the link below, there is a lot of literature about this compound(3,4,5-Trichloropyridine)Safety of 3,4,5-Trichloropyridine, illustrating the importance and wide applicability of this compound(33216-52-3).
Reference:
Bromide – Wikipedia,
bromide – Wiktionary