Extracurricular laboratory: Synthetic route of 1001-26-9

In addition to the literature in the link below, there is a lot of literature about this compound(Ethyl 3-Ethoxy-2-Propenoate)Reference of Ethyl 3-Ethoxy-2-Propenoate, illustrating the importance and wide applicability of this compound(1001-26-9).

Heterocyclic compounds can be divided into two categories: alicyclic heterocycles and aromatic heterocycles. Compounds whose heterocycles in the molecular skeleton cannot reflect aromaticity are called alicyclic heterocyclic compounds. Compound: 1001-26-9, is researched, Molecular C7H12O3, about Green synthesis of Levofloxacin, the main research direction is synthesis Levofloxacin ethyl ethoxyacrylate.Reference of Ethyl 3-Ethoxy-2-Propenoate.

New process for preparing Levofloxacin was described. The target was prepared from (2, 3, 4, 5)-fluorobenzoic chloride, which reacted with Et 3-ethoxyacrylate, amination with S-(+)-2-aminopropanol, cyclization, hydrolysis and condensation with N-Me piperazine. The total yield was 50.15%. The process has many advantages, such as simple operation, less environmental pollution. In line with the green chem. development direction, it deserves further research and popularization.

In addition to the literature in the link below, there is a lot of literature about this compound(Ethyl 3-Ethoxy-2-Propenoate)Reference of Ethyl 3-Ethoxy-2-Propenoate, illustrating the importance and wide applicability of this compound(1001-26-9).

Reference:
Bromide – Wikipedia,
bromide – Wiktionary