Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 630-17-1, name is 1-Bromo-2,2-dimethylpropane, This compound has unique chemical properties. The synthetic route is as follows., Quality Control of 1-Bromo-2,2-dimethylpropane
To a solution of 0,8g(33,10 mmol)of magnesium turnings and 2,0g(13,2 mmol)of 1- bromo-2,2-dimethylpropane in 10 mL diethyl ether was added a solution of 1.42 g (7.76 mmol) of 4-bromostyrene and 69 mg (0.13 [MMOL) OF NI] (dppf) [C12.] The resulting reaction mixture was heated at refluc for 8 h. The reaction was quenched with [50%] saturated NH4Cl, and was extracted with MTBE (2 x 150 mL). The combined extractions were washed with water, dried and concentrated. Flash chromatography on a Biotage 40M cartridge with hexanes as the eluant afforded 1.74 g of the title compound [: LH NMR (500 MHZ) a 0.] 93 (s, 9H), 2.49 (s, 2H), 5.20 (d, J = 10.9, 1H), 5.73 (d, [J] = 17.6, 1H), 6.72 (dd, [JL] [= 17.] 6, J2 [= 10.] 8,1H), 7.10 (d, J = 8.2, 2H), 7.33 (d, J = 8.0, 2H); ESI-MS 161 (M+H); LC-1: 4.4 min.
According to the analysis of related databases, 630-17-1, the application of this compound in the production field has become more and more popular.
Reference:
Patent; MERCK & CO., INC.; WO2004/35538; (2004); A1;,
Bromide – Wikipedia,
bromide – Wiktionary