Application of 10269-01-9,Some common heterocyclic compound, 10269-01-9, name is (3-Bromophenyl)methanamine, molecular formula is C7H8BrN, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
1B (100 mg, 0.40 mmol),3-bromobenzylamine (74 mg, 0.40 mmol) and potassium carbonate (50 mg, 0.36 mmol)DMF was distilled off under reduced pressure. Separated with DCM-MeOH (40:1) as eluent,A white solid (41 mg, 27.9%) was obtained.
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route (3-Bromophenyl)methanamine, its application will become more common.
Reference:
Patent; Shanghai Jiao Tong University; Mao Zhenmin; Wang Yaolin; Zhan Xiaoping; (15 pag.)CN109593066; (2019); A;,
Bromide – Wikipedia,
bromide – Wiktionary