Adding a certain compound to certain chemical reactions, such as: 3975-77-7, name is 2-Bromo-1,3,5-tri-tert-butylbenzene, belongs to bromides-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 3975-77-7, Recommanded Product: 3975-77-7
2,4,6-Tri-tert-butylbenzoicacid (mes*CO2H, S3). The Br/Liinterchange reaction between mes*Br and n-BuLi in Et2O (see above)was carried out according to the protocol of Staab and LauerS9 but with a reaction period shortened to lessthan 1 hour at room temperature. Afterpouring onto solid CO2 andaqueous workup, the acid fraction furnished mes*CO2H (S3, crude yield up to 75%); m.p.284-286 C (toluene), Ref. S9: 298-300 C.1H NMR (80 MHz, 2,4,6-Tri-tert-butylbenzoicacid (mes*CO2H, S3). The Br/Liinterchange reaction between mes*Br and n-BuLi in Et2O (see above)was carried out according to the protocol of Staab and LauerS9 but with a reaction period shortened to lessthan 1 hour at room temperature. Afterpouring onto solid CO2 andaqueous workup, the acid fraction furnished mes*CO2H (S3, crude yield up to 75%); m.p.284-286 C (toluene), Ref. S9: 298-300 C.1H NMR (80 MHz,
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 2-Bromo-1,3,5-tri-tert-butylbenzene, other downstream synthetic routes, hurry up and to see.
Reference:
Article; Knorr, Rudolf; Rossmann, Eva C.; Knittl, Monika; Boehrer, Petra; Tetrahedron; vol. 70; 34; (2014); p. 5332 – 5338;,
Bromide – Wikipedia,
bromide – Wiktionary