In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 4117-09-3 as follows. Recommanded Product: 4117-09-3
To a suspension of 6 (40 mg, 0.075 mmol) and K2CO3 (51.2 mg, 0.373 mmol) in DMF (1 mL) was added 7-bromohept-1-ene (39.6 mg, 0.224 mmol). The reaction was stirred at 40 C for 5 h. The reaction mixture was cooled to rt and purified by flash chromatography (silica gel; linear gradient 0-10% MeOH-CH2Cl2) to provide S4f (42 mg, 77%).
According to the analysis of related databases, 4117-09-3, the application of this compound in the production field has become more and more popular.
Reference:
Article; Donnell, Andrew F.; Zhang, Yong; Stang, Erik M.; Wei, Donna D.; Tebben, Andrew J.; Perez, Heidi L.; Schroeder, Gretchen M.; Pan, Chin; Rao, Chetana; Borzilleri, Robert M.; Vite, Gregory D.; Gangwar, Sanjeev; Bioorganic and Medicinal Chemistry Letters; vol. 27; 23; (2017); p. 5267 – 5271;,
Bromide – Wikipedia,
bromide – Wiktionary