Continuously updated synthesis method about Sodium 2-bromoethanesulphonate

At the same time, in my other blogs, there are other synthetic methods of this type of compound, Sodium 2-bromoethanesulphonate, and friends who are interested can also refer to it.

4263-52-9, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 4263-52-9 name is Sodium 2-bromoethanesulphonate, This compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.

Sodium-2-bromoethane sulfonate (41 1 mg, 1.95 mmol) and powdered K2C03 (269 mg, 1.95 mmol) are suspended in 3ml_ of dry DMF under argon atmosphere. N-methyldodecylamine (298 mg, 1.50 mmol) is added and the mixture stirred at 130C overnight. The volatiies are removed on a rotary evaporator and the residue purified by preparative HPLC and dried in high vacuum to yield 342 mg (74%) of 1q as a white solid.1H-NMR (300 MHz, CDCI3): delta = 0.81 (t, J = 6.4, 3H), 1.10-1.35 (m, 18H), 1 .70 (m, 2H), 2.88 (s), 2.89 (s,? = 3H), 3.0-3.45 (m, 5H), 3.55 (m, 1 H), 8.46 (br. s, 1 H), 8.89 (br. s, 1 H).MS (ESI): 308.2 (M+H+), 325.3 (M+NH4+), 615.4 (2M+H+).

At the same time, in my other blogs, there are other synthetic methods of this type of compound, Sodium 2-bromoethanesulphonate, and friends who are interested can also refer to it.

Reference:
Patent; JADO TECHNOLOGIES GMBH; TECHNISCHE UNIVERSITAeT DRESDEN; SCHLECHTINGEN, Georg; KNOeLKER, Hans-Joachim; FRIEDRICHSON, Tim; JENNINGS, Gary; BRAXMEIER, Tobias; WO2012/160187; (2012); A1;,
Bromide – Wikipedia,
bromide – Wiktionary