2695-47-8, name is 6-Bromo-1-hexene, belongs to bromides-buliding-blocks compound, is considered to be a conventional heterocyclic compound, which is widely used in drug synthesis. The chemical synthesis route is as follows. HPLC of Formula: C6H11Br
To a suspension of tosylamide (50.25 g, 293.5 mmol) and K2CO3 (17.28 g, 125.0 mmol) inDMSO (250 ml) was added 6-bromo-1-hexene (S3, 13.36 ml, 100.0 mmol) at room temperature.After stirring for 15 h at room temperature, the reaction mixture was filtered through a shortplug of Celite and partitioned between diethyl ether and H2O. The aqueous phases wereextracted twice with diethyl ether. The combined organic phases were washed with brine, driedover MgSO4, filtered and concentrated under reduced pressure. The residue was purified byflash column chromatography (20% EtOAc/hexane) to afford S4 (20.05 g, 78.15 mmol, 78%) asa yellow oil.
The synthetic route of 2695-47-8 has been constantly updated, and we look forward to future research findings.
Reference:
Article; Orihara, Kensuke; Kawagishi, Fumiki; Yokoshima, Satoshi; Fukuyama, Tohru; Synlett; vol. 29; 6; (2018); p. 769 – 772;,
Bromide – Wikipedia,
bromide – Wiktionary