68322-84-9, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 68322-84-9 name is 2-Bromo-1-fluoro-4-(trifluoromethyl)benzene, This compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.
A deoxygenated solution of tert-butyl 2, 5-dihydro-lH-pyrrole-l- carboxylate (3.38 g, 20.0 mmol, 10.0 equiv), [2-BROMO-1-FLUORO-4-] (trifluoromethyl) benzene (486 mg, 2.00 mmol, 1 equiv), N, N diisopropylethylamine (1.39 mL, 8.00 mmol, 4.00 equiv), tri-o-
At the same time, in my other blogs, there are other synthetic methods of this type of compound, 2-Bromo-1-fluoro-4-(trifluoromethyl)benzene, and friends who are interested can also refer to it.
Reference:
Patent; MERCK & CO., INC.; WO2003/105855; (2003); A1;,
Bromide – Wikipedia,
