The origin of a common compound about 3814-30-0

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, (Bromomethyl)cyclopentane, other downstream synthetic routes, hurry up and to see.

Adding a certain compound to certain chemical reactions, such as: 3814-30-0, name is (Bromomethyl)cyclopentane, belongs to bromides-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 3814-30-0, Computed Properties of C6H11Br

To a solution of 3-(tetrahydro-2H-pyran-4-yI)imidazo[1 ,5-a]pyrazin-8(7H)-one (400 mg, 1 .82 mmol) in anhydrous DMF (5 mL) was added K2003 (503 mg, 3.64mmol) and (bromomethyl)cyclopentane (445 mg, 2.73 mmol). The reaction mixture was stirred at 6000 for 16 hours. The mixture was filtered and the filtrate was purified bypreparative LC-MS to afford 7-(cyclopentylmethyl)-3-(tetrahydro-2H-pyran-4-yl)i midazo[1 ,5- a]pyrazin-8(7H)-one 290 mg (53%).1H NMR (DMSO-d6, 400 Mhz): 7.62 (s, 1H), 7.49 (d, J= 6.0 Hz, 1H), 6.90 (d, J= 6.0 Hz,1H), 3.91-3.88 (m, 2H), 3.69 (d, J= 7.6Hz, 2H), 3.48-3.43 (m, 2H), 3.42-3.31 (m, 1H), 2.27-2.24 (m, 1H), 1.78-1.73 (m, 4H), 1.58-1.44 (m, 6H), 1.21-1.20 (m, 2H).LC-MS: (mlz) 302.2 (MH) tR (minutes, method 3) = 2.29 minutes

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, (Bromomethyl)cyclopentane, other downstream synthetic routes, hurry up and to see.

Reference:
Patent; H. LUNDBECK A/S; KEHLER, Jan; RASMUSSEN, Lars, Kyhn; LANGGARD, Morten; JESSING, Mikkel; VITAL, Paulo, Jorge, Vieira; JUHL, Karsten; (159 pag.)WO2016/174188; (2016); A1;,
Bromide – Wikipedia,
bromide – Wiktionary