Reference of 17247-58-4, The chemical industry reduces the impact on the environment during synthesis 17247-58-4, name is (Bromomethyl)cyclobutane, I believe this compound will play a more active role in future production and life.
Sodium sulfite (1.3 g; WAKO), ethanol (3.9 mL), and water (5.8 mL) were added to (bromomethyl)cyclobutane (0.8 mL; Ald), the resulting mixture was stirred at 100 C. for 2 hours, and the solvent was evaporated under reduced pressure. Toluene (10 mL), DMF (20 muL), and thionyl chloride (1.9 mL; TCI) were successively added to the residue, the resulting mixture was stirred at 110 C. for 5 hours, and the solvent was evaporated under reduced pressure. This residue was used instead of ethanesulfonyl chloride described in the step of Reference Example N-2 to give the title compound.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, (Bromomethyl)cyclobutane, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; ASAHI KASEI PHARMA CORPORATION; US2010/261701; (2010); A1;,
Bromide – Wikipedia,
bromide – Wiktionary