Electric Literature of 105309-59-9, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 105309-59-9 name is Tetrakis(4-bromophenyl)methane, This compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.
Cz (2.5 g, 8.9 mmol), intermediate TBrBen (2.8 g, 4.5 mmol), CuI (0.19 g, 1.0 mmol) and K3PO4 (1.69 g, 8.0 mmol) were added to 100 mL of toluene.The reaction was carried out under argon gas protection and reflux for 24 hours.After removing the solvent, the residue was extracted with dichloromethane (3×100 mL).The organic phases were combined and dried over anhydrous magnesium sulfate.The residue obtained by concentration was purified by column chromatography using dichloromethane: n-hexane (7:3) as eluent to afford product DCzCBr (2.7 g, yield 50.3%).Identification of intermediates by mass spectrometry,The result is:
At the same time, in my other blogs, there are other synthetic methods of this type of compound, Tetrakis(4-bromophenyl)methane, and friends who are interested can also refer to it.
Reference:
Patent; Yangtze Normal University; Yang Yezi; Yao Chuang; Sun Changqing; (13 pag.)CN108752320; (2018); A;,
Bromide – Wikipedia,
bromide – Wiktionary