Related Products of 89523-51-3, These common heterocyclic compound, 89523-51-3, name is 5-Bromobenzo[c]phenanthrene, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
Argon atmosphere, 2-nitro-phenylboronic acid 2.00g, 5-bromo-benzo [c] phenanthrene, 6.12g, tetrakis triphenylphosphine palladium (0) 0.462g, DME 80mL, 2M aqueous sodium carbonate solution in the flask was added 40mL and the mixture was heated and stirred 24 hr reflux. after cooling to room temperature (25 ), after the reaction solution was extracted using toluene, and removing the water layer, an organic layer was washed with saturated aqueous sodium chloride. The organic layer was dried over magnesium sulfate, concentrated, and the residue was purified by silica gel column chromatography to give 5- (2-nitro-phenyl) benzo [c] phenanthrene was obtained a 5.72g.
The synthetic route of 89523-51-3 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Idemitsu Kosan Corporation; Kawamura, Masahiro; Mizuki, Yumiko; Ito, Hirokazu; Hayama, Tomoharu; Haketa, Tasuku; (69 pag.)KR2015/126340; (2015); A;,
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