52997-43-0, The chemical industry reduces the impact on the environment during synthesis 52997-43-0, name is 7-(Bromomethyl)pentadecane, I believe this compound will play a more active role in future production and life.
In a two-necked RBF (100 mL), compound 3 (3.34 g, 10 mmol), KOH(2.81 g, 50 mmol) and KI (0.17 g, 1 mmol) were mixed in the dry THF(50 mL). The mixture was degassed with N2 flow for 20 min, and 1-bromo-2-hexyldecane (3.66 g, 12 mmol) was added. The solution wasstirred at 65 C for 12 h under N2 before it was cooled to room temperature.The organic layer was extracted with DCM and dried overNa2SO4, and the solvent was removed by rotary evaporation. The residuewas purified by silica gel chromatography (PE as the eluent) toyield the yellow viscous liquid (5.14 g, 92%). 1H NMR (400 MHz,CDCl3) delta 7.54 (d, J=8.4 Hz, 1H), 7.47 (s, 1H), 7.25 (m, 3H), 7.08 (s,1H), 7.06-7.04 (m, 1H), 4.05 (d, J=7.5 Hz, 2H), 2.04 (s, 1H),1.29-1.23 (m, 24H), 0.89-0.84 (m, 6H). 13C NMR (100 MHz, CDCl3) delta145.81, 142.05, 139.07, 138.47, 127.99, 124.58, 123.70, 122.37,120.57, 119.80, 115.82, 114.62, 113.05, 107.11, 49.77, 38.29, 31.86,31.78, 31.62, 29.90, 29.70, 29.58, 29.51, 29.27, 26.38, 26.35, 22.65,22.62, 14.09, 14.06. MALDI-TOF-MS (m/z) 559.27 for [M]+.
The chemical industry reduces the impact on the environment during synthesis 52997-43-0. I believe this compound will play a more active role in future production and life.
Reference:
Article; Zhou, Xingbao; Lu, Jurong; Huang, Hongyan; Yun, Yikai; Li, Zhaoning; You, Fei; Zhao, Baomin; Qin, Tianshi; Gao, Deqing; Huang, Wei; Dyes and Pigments; vol. 160; (2019); p. 16 – 24;,
Bromide – Wikipedia,
bromide – Wiktionary