Preparation of aromatic sulfonyl halides was written by Jenkins, F. E.;Hambly, A. N.. And the article was included in Australian Journal of Chemistry in 1953.Recommanded Product: 454-65-9 This article mentions the following:
The following RC6H4SO2Cl are prepared by chlorination of the RSO2H, which are obtained by the modified Gattermann procedure (addition of the diazonium sulfate of the appropriate amine to a suspension of Cu powder in dilute H2SO4 saturated with SO2) (R, % yield given): m-Me, 50, b0.3 77-8° (sulfonamide, m. 108.5-9.5°); ο-MeO, 51; m-Cl, 50; m-Br, 54. Refluxing the RC6H4SO2Cl with excess of a saturated aqueous solution of KF gave RC6H4SO2F: m-Me, 85, b1.4 78.5-79°, n25D 1.4909; ο-MeO, 42, m. 39-40°; p-AcNH (I), 47, m. 176°; m-Cl, 63, b0.8 69-70°, n25D 1.5114; m-Br, 63, b1.0 90°, n25D 1.5358; p-O2N (II), 65, m. 77.5-8.5°. I is best prepared in aqueous dioxane. Reduction of II with Sn and HCl gives p-H2NC6H4SO2F (45%), m. 72-3°, converted into I by Ac2O in AcOH. In the experiment, the researchers used many compounds, for example, 3-Bromobenzene-1-sulfonyl fluoride (cas: 454-65-9Recommanded Product: 454-65-9).
3-Bromobenzene-1-sulfonyl fluoride (cas: 454-65-9) belongs to organobromine compounds. Most of the natural organobromine compounds are produced by marine organisms, and several brominated metabolites with antibacterial, antitumor, antiviral, and antifungal activity have been isolated from seaweed, sponges, corals, molluscs, and others. The reactivity of organobromine compounds resembles but is intermediate between the reactivity of organochlorine and organoiodine compounds. For many applications, organobromides represent a compromise of reactivity and cost.Recommanded Product: 454-65-9
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary