Synthesis of trans-4-triazolyl-substituted 3-hydroxypiperidines was written by Harmsen, Rianne A. G.;Sydnes, Leiv K.;Tornroos, Karl W.;Haug, Bengt Erik. And the article was included in Synthesis in 2011.Application of 14425-64-0 This article mentions the following:
The synthesis of tert-Bu trans-4-ethynyl-3-hydroxypiperidine-1-carboxylate is described via regioselective ring-opening of a racemic N-Boc-protected 7-oxa-3-azabicyclo[4.1.0]heptane, and serves as a new scaffold for the preparation of substituted piperidines. The terminal alkyne is converted into 1,4- and 1,5-disubstituted 1,2,3-triazoles through 1,3-dipolar cycloaddition reactions with organic azides. In the experiment, the researchers used many compounds, for example, 1-(2-Bromoethyl)-4-methoxybenzene (cas: 14425-64-0Application of 14425-64-0).
1-(2-Bromoethyl)-4-methoxybenzene (cas: 14425-64-0) belongs to organobromine compounds. Organo bromine compounds are versatile compounds and are widely used in diverse fields. Organo bromine derivatives are used in the dye sector, as an indicator in analytical chemistry (Bromothymol blue is a popular indicator). When the molecular ion is detected, the bromine and chlorine isotope patterns are very distinct, but caution is to be exercised for certain mixed chlorinated/brominated compounds, which can look similar to homohalogen patterns.Application of 14425-64-0
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary